Gene Information gene info

GENE:RAP1GDS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAP1GDS1
FullNmae Rap1 GTPase-GDP dissociation stimulator 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9859
EnsembleID ENSG00000138698
Uniprot P52306

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAP1GDS1 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAP1GDS1 GO:0003300,GO:0005085,GO:0005515,GO:0005634,GO:0005739,GO:0005783,GO:0005829,GO:0005829,GO:0010821,GO:0014829,GO:0031034,GO:0032471,GO:0034504,GO:0043547,GO:0051561,GO:0070062,GO:0070376,GO:0080120,GO:0086098,GO:1904464

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HRAS RAP1GDS1 11948427 23180781 physical association anti tag coimmunoprecipitation,two hybrid,gst pull down InnateDB
KRAS RAP1GDS1 11948427 23180781 physical association two hybrid InnateDB
RAP1GDS1 RAP1A 11948427 23180781 physical association two hybrid InnateDB
RAC1 RAP1GDS1 11948427 23180781 physical association two hybrid InnateDB
RAP1GDS1 RHOA 11948427 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR RAP1GDS1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RAP1GDS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RAP1GDS1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RAP1GDS1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RAP1GDS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000192A75 RAP1GDS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF RAP1GDS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002AAD6B RAP1GDS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA RAP1GDS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC RAP1GDS1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HRAS RAP1GDS1 25361965 interaction type N/A PTMCode2
RAP1GDS1 HRAS 25361965 interaction type N/A PTMCode2
RAP1GDS1 RAC1 25361965 interaction type N/A PTMCode2
RAC1 RAP1GDS1 25361965 interaction type N/A PTMCode2
RAP1GDS1 RAP1A 25361965 interaction type N/A PTMCode2
RAP1A RAP1GDS1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC42 RAP1GDS1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
KRAS RAP1GDS1 11948427 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PPP1R2B RAP1GDS1 25348397 N/A physical interaction ComPPI
RAC1 RAP1GDS1 11948427 14525934 20936779 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DUSP23 RAP1GDS1 25348397 N/A physical interaction ComPPI
HRAS RAP1GDS1 11948427 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RHOC RAP1GDS1 25348397 N/A physical interaction ComPPI
RHOA RAP1GDS1 11948427 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAP1GDS1 RAP1A 11948427 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RAP1GDS1 KIFAP3 14525934 25348397 8900189 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAP1GDS1 ZNF451 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAP1GDS1 MBIP 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAP1GDS1 NRAS 11948427 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAP1GDS1 EGFR 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
RAP1GDS1 DCPS 25348397 N/A physical interaction ComPPI
RAP1GDS1 GAPDH 25348397 N/A physical interaction ComPPI
RAP1GDS1 GINS3 25348397 N/A physical interaction ComPPI
RAP1GDS1 HSPA1L 25348397 N/A physical interaction ComPPI
RAP1GDS1 NAE1 25348397 N/A physical interaction ComPPI
RAP1GDS1 OLA1 25348397 N/A physical interaction ComPPI
RAP1GDS1 PAFAH1B2 25348397 N/A physical interaction ComPPI
RAP1GDS1 PPP1R2 25348397 N/A physical interaction ComPPI
RAP1GDS1 PTMA 25348397 N/A physical interaction ComPPI
RAP1GDS1 ABHD14A 25348397 N/A physical interaction ComPPI
RAP1GDS1 ASNS 25348397 N/A physical interaction ComPPI
RAP1GDS1 CAPN1 25348397 N/A physical interaction ComPPI
RAP1GDS1 ECHS1 25348397 N/A physical interaction ComPPI
RAP1GDS1 GMDS 25348397 N/A physical interaction ComPPI
RAP1GDS1 GSS 25348397 N/A physical interaction ComPPI
RAP1GDS1 HSPA5 25348397 N/A physical interaction ComPPI
RAP1GDS1 MSN 25348397 N/A physical interaction ComPPI
RAP1GDS1 PDIA4 25348397 N/A physical interaction ComPPI
RAP1GDS1 PFAS 25348397 N/A physical interaction ComPPI
RAP1GDS1 PPP5C 25348397 N/A physical interaction ComPPI
RAP1GDS1 TATDN1 25348397 N/A physical interaction ComPPI
RAP1GDS1 UBQLN1 25348397 N/A physical interaction ComPPI
RAP1GDS1 USP14 25348397 N/A physical interaction ComPPI
RAP1GDS1 VCL 25348397 N/A physical interaction ComPPI
RAP1GDS1 YWHAE 25348397 N/A physical interaction ComPPI
RAP1GDS1 DOC2A 25348397 N/A physical interaction ComPPI
RAP1GDS1 PLEKHB1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAP1GDS1 MOV10 25348397 N/A physical interaction ComPPI
RAP1GDS1 DIRAS3 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAB34 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAB34 25348397 N/A physical interaction ComPPI
RAP1GDS1 RASD2 25348397 N/A physical interaction ComPPI
RAP1GDS1 HDAC7 25348397 N/A physical interaction ComPPI
RAP1GDS1 APBB2 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAB1C 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAB1B 25348397 N/A physical interaction ComPPI
RAP1GDS1 SNX24 25348397 N/A physical interaction ComPPI
RAP1GDS1 GNAI1 25348397 N/A physical interaction ComPPI
RAP1GDS1 SEPTIN12 25348397 N/A physical interaction ComPPI
RAP1GDS1 TSC22D4 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAB31 25348397 N/A physical interaction ComPPI
RAP1GDS1 RASL10A 25348397 N/A physical interaction ComPPI
RAP1GDS1 SEPTIN6 25348397 N/A physical interaction ComPPI
RAP1GDS1 BAIAP2 25348397 N/A physical interaction ComPPI
RAP1GDS1 HSPB9 25348397 N/A physical interaction ComPPI
RAP1GDS1 C2ORF48 25348397 N/A physical interaction ComPPI
RAP1GDS1 UNC45A 25348397 N/A physical interaction ComPPI
RAP1GDS1 NTRK1 25348397 N/A physical interaction ComPPI
RAP1GDS1 PUF60 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAP1GDS1 CDK2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAP1GDS1 DIRAS1 25348397 N/A physical interaction ComPPI
RAP1GDS1 UBTF 25348397 N/A physical interaction ComPPI
RAP1GDS1 DIRAS2 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAC3 25348397 N/A physical interaction ComPPI
RAP1GDS1 PRDM10 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAP2C 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAP1B 25348397 N/A physical interaction ComPPI
RAP1GDS1 DNAL1 25348397 N/A physical interaction ComPPI
RAP1GDS1 RHOF 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAB15 25348397 N/A physical interaction ComPPI
RAP1GDS1 RABL3 25348397 N/A physical interaction ComPPI
RAP1GDS1 RBM42 25348397 N/A physical interaction ComPPI
RAP1GDS1 IRGC 25348397 N/A physical interaction ComPPI
RAP1GDS1 VASH1 25348397 N/A physical interaction ComPPI
RAP1GDS1 NKIRAS2 25348397 N/A physical interaction ComPPI
RAP1GDS1 IL13RA1 25348397 N/A physical interaction ComPPI
RAP1GDS1 RAC2 25348397 N/A physical interaction ComPPI
RAP1GDS1 ARL4C 25348397 N/A physical interaction ComPPI
RAP1GDS1 NT5C 25348397 N/A physical interaction ComPPI
RAP1GDS1 TRIM25 25348397 N/A physical interaction ComPPI
RAP1GDS1 IFT27 24234451 25348397 27173435 association anti tag coimmunoprecipitation ComPPI,IntAct
HSPA9 RAP1GDS1 25348397 N/A physical interaction ComPPI
GNAZ RAP1GDS1 25348397 N/A physical interaction ComPPI
CANX RAP1GDS1 24234451 30021884 physical association cross-linking study IntAct
RAP1GDS1 RHOA 11948427 20709748 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 RAC2 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 RAC1 11948427 20709748 20936779 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 CDC42 20936779 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 RAP1B 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 RAP1A 11948427 20709748 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 KRAS 11948427 20709748 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 RHOC 21242305 27898060 stimulant N/A OmniPath
RAP1GDS1 RHOB 21242305 27898060 stimulant N/A OmniPath

Visualization