GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
MTCH2 |
| FullNmae |
mitochondrial carrier 2 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:17587 |
| EnsembleID |
ENSG00000109919 |
| Uniprot |
Q9Y6C9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| MTCH2 |
mpt |
39227319 |
The interplay between MTCH2 and subunit j coordinates MOMP and PTP to mediate the occurrence of mitochondrial permeability transition. |
retulator signature |
| MTCH2 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| MTCH2 |
GO:0005515,GO:0005634,GO:0005739,GO:0005741,GO:0010635,GO:0016020,GO:0016020,GO:0032977,GO:0043065,GO:0043065,GO:0045040,GO:0055088,GO:0070585,GO:2000738 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
MTCH2 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
MTCH2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
MTCH2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
MTCH2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
MTCH2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
MTCH2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
MTCH2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS000003ABC4 |
MTCH2 |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS00000BE495 |
MTCH2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00005651EE |
MTCH2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS000000B1C9 |
MTCH2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS000001C659 |
MTCH2 |
23623609
25416803
|
mrna cleavage,inhibition |
western blot,miRNA interference luciferase reporter assay |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| CHCHD2 |
MTCH2 |
24234451
25348397
27499296
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| NDUFB9 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP5PO |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RPN1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP5F1B |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TOMM22 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MCM2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| SLC7A1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CD44 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBC |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NTRK1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PVR |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FMNL1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PHB |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HNRNPU |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PTPN5 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DUSP4 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| VDAC1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PDHA1 |
MTCH2 |
24234451
25348397
29128334
|
association |
cross-linking study,physical interaction |
ComPPI,IntAct |
| RAB1A |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CLTC |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| VDAC2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP1A1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP1B1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PHB2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RNF2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UQCRC2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP2A2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PLIN3 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| XRN1 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DUSP22 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| BCAM |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ESR1 |
MTCH2 |
14525934
15604093
25348397
|
N/A |
two hybrid,physical interaction,two hybrid |
ComPPI,HPRD |
| CACNG2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GNAI2 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| WNT4 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TOMM40 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP5F1C |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP5F1A |
MTCH2 |
24234451
25348397
27499296
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| SLC25A3 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| OFD1 |
MTCH2 |
24234451
25348397
26638075
|
association |
physical interaction,proximity-dependent biotin identification |
ComPPI,IntAct |
| VDAC3 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NDUFA6 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NDUFB8 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATP5MG |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FBXO6 |
MTCH2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
ALDH3A2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
ATP5PB |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
NDUFB5 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
NDUFA12 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
NDUFA2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
NDUFS1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
NDUFS2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
NDUFS3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
SDHB |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
SDHC |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
SGPL1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
UBXN8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
NDUFA4 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
APOOL |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
SLC1A5 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MTCH2 |
OXCT1 |
24234451
25348397
27499296
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| MTCH2 |
COX6B1 |
24234451
25348397
27499296
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| MTCH2 |
BID |
20436477
21295084
27898060
|
stimulant |
N/A |
OmniPath |
Visualization