Gene Information gene info

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GENE：ACAA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACAA2
FullNmae acetyl-CoA acyltransferase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:83
EnsembleID ENSG00000167315
Uniprot P42765

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACAA2 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACAA2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACAA2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ACAA2 GO:0003723,GO:0003985,GO:0003985,GO:0003986,GO:0003988,GO:0003988,GO:0005515,GO:0005739,GO:0005739,GO:0005739,GO:0005759,GO:0006635,GO:0006635,GO:0006695,GO:0016290,GO:0047617,GO:0071456,GO:0102991,GO:1901029,GO:1902109

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACAA2 hsa:10449 path:hsa00062 Fatty acid elongation - Homo sapiens (human)
ACAA2 hsa:10449 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
ACAA2 hsa:10449 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
ACAA2 hsa:10449 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ACAA2 hsa:10449 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ACAA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ACAA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 ACAA2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 ACAA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075C1E1 ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 ACAA2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D ACAA2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E ACAA2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ACAA2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 ACAA2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TAX1BP3 ACAA2 25348397 N/A physical interaction ComPPI
SGTA ACAA2 25348397 N/A physical interaction ComPPI
VAMP2 ACAA2 25348397 N/A physical interaction ComPPI
CFL1 ACAA2 25348397 N/A physical interaction ComPPI
TP53BP1 ACAA2 25348397 N/A physical interaction ComPPI
KEAP1 ACAA2 25348397 N/A physical interaction ComPPI
SF3B4 ACAA2 25348397 N/A physical interaction ComPPI
PFN1 ACAA2 25348397 N/A physical interaction ComPPI
PGD ACAA2 25348397 N/A physical interaction ComPPI
NTRK1 ACAA2 25348397 N/A physical interaction ComPPI
ENO1 ACAA2 25348397 N/A physical interaction ComPPI
P4HB ACAA2 25348397 N/A physical interaction ComPPI
PRDX1 ACAA2 25348397 N/A physical interaction ComPPI
TERT ACAA2 25348397 N/A physical interaction ComPPI
VDAC1 ACAA2 25348397 N/A physical interaction ComPPI
TAGLN ACAA2 25348397 N/A physical interaction ComPPI
EWSR1 ACAA2 25348397 N/A physical interaction ComPPI
RDX ACAA2 25348397 N/A physical interaction ComPPI
VDAC2 ACAA2 25348397 N/A physical interaction ComPPI
HNRNPA2B1 ACAA2 25348397 N/A physical interaction ComPPI
ATP1B1 ACAA2 25348397 N/A physical interaction ComPPI
SCP2 ACAA2 10856712 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ACAA2 APP 25348397 N/A physical interaction ComPPI
ACAA2 ACAT1 25348397 N/A physical interaction ComPPI
ACAA2 ZFR 25348397 N/A physical interaction ComPPI
ACAA2 TIAL1 25348397 N/A physical interaction ComPPI
ACAA2 RTN4 25348397 N/A physical interaction ComPPI
ACAA2 TOMM40 25348397 N/A physical interaction ComPPI
ACAA2 ACO2 25348397 N/A physical interaction ComPPI
ACAA2 AK2 25348397 N/A physical interaction ComPPI
ACAA2 ALDOA 25348397 N/A physical interaction ComPPI
ACAA2 EZR 25348397 N/A physical interaction ComPPI
ACAA2 HNRNPA1 25348397 N/A physical interaction ComPPI
ACAA2 MSN 25348397 N/A physical interaction ComPPI
ACAA2 POFUT1 25348397 N/A physical interaction ComPPI
ACAA2 TAF15 25348397 N/A physical interaction ComPPI
ACAA2 TAGLN2 25348397 N/A physical interaction ComPPI
ACAA2 TKT 25348397 N/A physical interaction ComPPI
ACAA2 UCHL3 25348397 N/A physical interaction ComPPI
ACAA2 USP8 25348397 N/A physical interaction ComPPI
ACAA2 CSRP1 25348397 N/A physical interaction ComPPI
ACAA2 PGK1 25348397 N/A physical interaction ComPPI
ACAA2 SH3PXD2B 25348397 N/A physical interaction ComPPI
ACAA2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ACAA2 LAMTOR5 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ACAA2 HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ACAA2 PDK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FKBP2 ACAA2 25348397 N/A physical interaction ComPPI
TRMT61B ACAA2 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ACAA2 BNIP3 19136941 27898060 inhibition N/A OmniPath

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