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GENE：SLC39A14

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLC39A14
FullNmae solute carrier family 39 member 14
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20858
EnsembleID ENSG00000104635
Uniprot Q15043

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLC39A14 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLC39A14 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLC39A14 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
SLC39A14 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLC39A14 GO:0002062,GO:0005381,GO:0005384,GO:0005385,GO:0005385,GO:0005385,GO:0005765,GO:0005886,GO:0005886,GO:0006094,GO:0006882,GO:0008286,GO:0010817,GO:0015086,GO:0015093,GO:0015296,GO:0015701,GO:0016020,GO:0016323,GO:0016324,GO:0031901,GO:0031902,GO:0032869,GO:0033212,GO:0034755,GO:0045745,GO:0051344,GO:0055071,GO:0070574,GO:0071333,GO:0071421,GO:0071577,GO:0071577,GO:0071577,GO:0071578,GO:0071578,GO:0098656,GO:0098662,GO:0098739,GO:0140410,GO:0140410

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SLC39A14 hsa:23516 path:hsa04216 Ferroptosis - Homo sapiens (human)
SLC39A14 hsa:23516 path:hsa05010 Alzheimer disease - Homo sapiens (human)
SLC39A14 hsa:23516 path:hsa05012 Parkinson disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
STING1 SLC39A14 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 SLC39A14 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SLC39A14 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TFAP2C SLC39A14 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SLC39A14 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SLC39A14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB SLC39A14 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 SLC39A14 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000CBE63 SLC39A14 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000041CB9C SLC39A14 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000292B1 SLC39A14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 SLC39A14 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 SLC39A14 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 SLC39A14 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F SLC39A14 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 SLC39A14 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 SLC39A14 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 SLC39A14 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D SLC39A14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 SLC39A14 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SLC38A1 SLC39A14 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
CD81 SLC39A14 24234451 25348397 30024968 association anti bait coimmunoprecipitation ComPPI,IntAct
ADRB2 SLC39A14 25348397 N/A physical interaction ComPPI
ELAVL1 SLC39A14 25348397 N/A physical interaction ComPPI
TGOLN2 SLC39A14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 SLC39A14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TMEM216 SLC39A14 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
LAMP1 SLC39A14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STING1 SLC39A14 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC39A14 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
BDKRB1 SLC39A14 24234451 28298427 physical association ubiquitin reconstruction IntAct
STING1 SLC39A14 21903422 27898060 N/A N/A OmniPath

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