GENE:CYBRD1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CYBRD1 |
| FullNmae | cytochrome b reductase 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20797 |
| EnsembleID | ENSG00000071967 |
| Uniprot | Q53TN4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CYBRD1 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CYBRD1 | mpt | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CYBRD1 | GO:0005515,GO:0005765,GO:0005886,GO:0005886,GO:0006879,GO:0010039,GO:0016020,GO:0016324,GO:0016491,GO:0016722,GO:0031526,GO:0033215,GO:0042802,GO:0046872,GO:0055085,GO:0060586,GO:0070062,GO:0140571,GO:0140575,GO:0140576 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CYBRD1 | hsa:79901 | path:hsa04978 | Mineral absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CYBRD1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | CYBRD1 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| GATA1 | CYBRD1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CYBRD1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CYBRD1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | CYBRD1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009262D | CYBRD1 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001C11BC | CYBRD1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | CYBRD1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | CYBRD1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | CYBRD1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | CYBRD1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | CYBRD1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | CYBRD1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FA24D | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000116F83 | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A79D1 | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000334286 | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CE046 | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040780F | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D6605 | CYBRD1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AAA0 | CYBRD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | CYBRD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFBE3 | CYBRD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | CYBRD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D986D | CYBRD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | CYBRD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | CYBRD1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMNA | CYBRD1 | 25348397 | N/A | physical interaction | ComPPI |
| HMOX1 | CYBRD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RABAC1 | CYBRD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| FLNA | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VAPA | CYBRD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RAB7A | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| IQGAP1 | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STX4 | CYBRD1 | 21516116 24234451 25348397 25416956 25910212 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| NEDD4L | CYBRD1 | 25348397 | N/A | physical interaction | ComPPI |
| HDAC2 | CYBRD1 | 25348397 | N/A | physical interaction | ComPPI |
| CREB3 | CYBRD1 | 25348397 | N/A | physical interaction | ComPPI |
| PLP2 | CYBRD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| FKBP8 | CYBRD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CDYL | CYBRD1 | 25348397 | N/A | physical interaction | ComPPI |
| SYNPO | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GOSR2 | CYBRD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ACTR2 | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MYH9 | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LIMA1 | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DBN1 | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HDAC1 | CYBRD1 | 25348397 | N/A | physical interaction | ComPPI |
| GOLT1B | CYBRD1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
