GENE：HEBP2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | HEBP2 |
| FullNmae | heme binding protein 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:15716 |
| EnsembleID | ENSG00000051620 |
| Uniprot | Q9Y5Z4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| HEBP2 | mpt | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| HEBP2 | GO:0005515,GO:0005576,GO:0005737,GO:0005737,GO:0005739,GO:0020037,GO:0035578,GO:0070062 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | HEBP2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | HEBP2 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ESR1 | HEBP2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | HEBP2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | HEBP2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | HEBP2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | HEBP2 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | HEBP2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | HEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | HEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | HEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | HEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | HEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000008A99 | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000221168 | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CC20C | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048D44E | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F31F4 | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CC005 | HEBP2 | 24906430 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0874 | HEBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CCD18 | HEBP2 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | HEBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | HEBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | HEBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | HEBP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019F055 | HEBP2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PLEKHF2 | HEBP2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| HNRNPL | HEBP2 | 25348397 | N/A | physical interaction | ComPPI |
| LRPPRC | HEBP2 | 11827465 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| PDCD6 | HEBP2 | 14525934 16189514 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
| HEBP2 | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
| HEBP2 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| HEBP2 | LAMTOR5 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| HNRNPD | HEBP2 | 24234451 30021884 | physical association | cross-linking study | IntAct |