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GENE：HADH

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HADH
FullNmae hydroxyacyl-CoA dehydrogenase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4799
EnsembleID ENSG00000138796
Uniprot Q16836

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HADH mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HADH autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HADH GO:0003857,GO:0003857,GO:0005654,GO:0005737,GO:0005739,GO:0005739,GO:0005759,GO:0006635,GO:0006635,GO:0006635,GO:0009410,GO:0014823,GO:0016740,GO:0032868,GO:0042802,GO:0046676,GO:0050796,GO:0070403,GO:0120162

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HADH hsa:3033 path:hsa00062 Fatty acid elongation - Homo sapiens (human)
HADH hsa:3033 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
HADH hsa:3033 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
HADH hsa:3033 path:hsa00310 Lysine degradation - Homo sapiens (human)
HADH hsa:3033 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
HADH hsa:3033 path:hsa00650 Butanoate metabolism - Homo sapiens (human)
HADH hsa:3033 path:hsa01100 Metabolic pathways - Homo sapiens (human)
HADH hsa:3033 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP HADH 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR HADH 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HADH 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HADH 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 HADH 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 HADH 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 HADH 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 HADH 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D HADH 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016C318 HADH 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
APP HADH 25361965 interaction type N/A PTMCode2
HADH APP 25361965 interaction type N/A PTMCode2
HADH HADH 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STAT1 HADH 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK3 HADH 25348397 N/A physical interaction ComPPI
SLC2A4 HADH 10068455 25348397 27898060 N/A two hybrid,in vitro ComPPI,OmniPath
UBE2N HADH 25348397 N/A physical interaction ComPPI
NTRK1 HADH 25348397 N/A physical interaction ComPPI
PITPNA HADH 25348397 N/A physical interaction ComPPI
PSMA1 HADH 25348397 N/A physical interaction ComPPI
CLK1 HADH 25348397 N/A physical interaction ComPPI
PSMB8 HADH 25348397 N/A physical interaction ComPPI
FKBP2 HADH 25348397 N/A physical interaction ComPPI
ACAT2 HADH 25348397 N/A physical interaction ComPPI
SF1 HADH 25348397 N/A physical interaction ComPPI
CLIC4 HADH 25348397 N/A physical interaction ComPPI
CLIC3 HADH 25348397 N/A physical interaction ComPPI
MMAB HADH 25348397 N/A physical interaction ComPPI
HADH UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HADH APP 25348397 N/A physical interaction ComPPI
HADH ADH1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HADH MOV10 25348397 N/A physical interaction ComPPI
HADH NXF1 25348397 N/A physical interaction ComPPI
HADH ETFA 25348397 N/A physical interaction ComPPI
HADH ETFB 25348397 N/A physical interaction ComPPI
HADH PSMA2 25348397 N/A physical interaction ComPPI
HADH RSU1 25348397 N/A physical interaction ComPPI
HADH HSPD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB HADH 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct

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