GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
ABCB7
FullNmae
ATP binding cassette subfamily B member 7
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:48
EnsembleID
ENSG00000131269
Uniprot
O75027
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
ABCB7
mpt
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
ABCB7
cuproptosis
36313717
The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in Table S1.
Genes related to copper homeostasis pathway
ABCB7
cuproptosis
36505872
A total of 44 cuproptosis-related genes were extracted from known literature.
cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
ABCB7
GO:0005515,GO:0005524,GO:0005739,GO:0005743,GO:0005743,GO:0005743,GO:0006879,GO:0006879,GO:0006879,GO:0015232,GO:0015886,GO:0016226,GO:0016887,GO:0034755,GO:0042626,GO:0042803,GO:0055085,GO:0070455,GO:0070455,GO:0140466,GO:0140481,GO:1903331,GO:1903331,GO:1903427
KEGG Annotation:
GeneSymbol
GeneID
Pathway
Pathway Name
ABCB7
hsa:22
path:hsa02010
ABC transporters - Homo sapiens (human)
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
ABCB7
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
ABCB7
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
ABCB7
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
ABCB7
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
ABCB7
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F4
ABCB7
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
ABCB7
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
SPI1
ABCB7
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000521626
ABCB7
17612493
25416803
mrna cleavage,inhibition
array technology
TarBase
URS000033EBB8
ABCB7
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000040EE1D
ABCB7
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000016D2D4
ABCB7
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00002075FA
ABCB7
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000016FD1A
ABCB7
22291592
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000250A40
ABCB7
22291592
25416803
mrna cleavage,inhibition
clip
TarBase
URS000031D186
ABCB7
22291592
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000D2680
ABCB7
22291592
25416803
mrna cleavage,inhibition
clip
TarBase
URS00004283FE
ABCB7
22291592
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000170D8B
ABCB7
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075ABF4
ABCB7
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000C85B2
ABCB7
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00003FBC84
ABCB7
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00001C0099
ABCB7
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000006372A
ABCB7
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000355E82
ABCB7
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000041FA2C
ABCB7
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00005586D0
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS000019907A
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS0000137EDE
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS00000AB32B
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS000021202F
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS000075CC78
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS000075D814
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS00001012BC
ABCB7
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
RPN1
ABCB7
25348397
N/A
physical interaction
ComPPI
UBC
ABCB7
25348397
N/A
physical interaction
ComPPI
NTRK1
ABCB7
25348397
N/A
physical interaction
ComPPI
MYC
ABCB7
17314511
24234451
25348397
association
tandem affinity purification
ComPPI,IntAct
CFTR
ABCB7
25348397
N/A
physical interaction
ComPPI
ABCB7
PCK1
25348397
N/A
physical interaction
ComPPI
ABCB7
APP
25348397
N/A
physical interaction
ComPPI
ABCB7
MRPL10
25348397
N/A
physical interaction
ComPPI
ABCB7
PDCD6
25348397
N/A
physical interaction
ComPPI
ABCB7
NDUFB6
25348397
N/A
physical interaction
ComPPI
ABCB7
UQCRC1
25348397
N/A
physical interaction
ComPPI
ABCB7
MTCH1
25348397
N/A
physical interaction
ComPPI
ABCB7
ACAT1
25348397
N/A
physical interaction
ComPPI
ABCB7
FKBP8
25348397
N/A
physical interaction
ComPPI
ABCB7
RAB2A
25348397
N/A
physical interaction
ComPPI
ABCB7
YBX3
25348397
N/A
physical interaction
ComPPI
ABCB7
EPRS1
25348397
N/A
physical interaction
ComPPI
ABCB7
FAF2
25348397
N/A
physical interaction
ComPPI
ABCB7
NDUFA4
25348397
N/A
physical interaction
ComPPI
ABCB7
TRIM25
25348397
N/A
physical interaction
ComPPI
ABCB7
PCGF1
24234451
25348397
27505670
association
tandem affinity purification
ComPPI,IntAct
ABCB7
COX6B1
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
XAB2
ABCB7
24234451
30021884
physical association
cross-linking study
IntAct
Visualization