GENE:ACADVL
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ACADVL |
| FullNmae | acyl-CoA dehydrogenase very long chain |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:92 |
| EnsembleID | ENSG00000072778 |
| Uniprot | P49748 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ACADVL | mpt | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ACADVL | GO:0000062,GO:0001659,GO:0003995,GO:0004466,GO:0005515,GO:0005654,GO:0005730,GO:0005739,GO:0005739,GO:0005743,GO:0005759,GO:0009409,GO:0015980,GO:0017099,GO:0017099,GO:0030855,GO:0031966,GO:0033539,GO:0033539,GO:0033539,GO:0042645,GO:0042802,GO:0045717,GO:0046322,GO:0050660,GO:0090181 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ACADVL | hsa:37 | path:hsa00071 | Fatty acid degradation - Homo sapiens (human) |
| ACADVL | hsa:37 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| ACADVL | hsa:37 | path:hsa01212 | Fatty acid metabolism - Homo sapiens (human) |
| ACADVL | hsa:37 | path:hsa04936 | Alcoholic liver disease - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ACADVL | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ACADVL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ACADVL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ACADVL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ACADVL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ACADVL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PDE4DIP | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| SOCS3 | ACADVL | 22093833 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| MCM2 | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| APC | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | ACADVL | 16212417 24234451 25348397 | physical association | surface plasmon resonance,physical interaction,surface plasmon resonance array | ComPPI,IntAct |
| METAP2 | ACADVL | 18337751 24234451 25348397 | association | biochemical | ComPPI,IntAct |
| PA2G4 | ACADVL | 18337751 24234451 25348397 | association | biochemical | ComPPI,IntAct |
| CFTR | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| CYP1A1 | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| NPPA | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| GPHN | ACADVL | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PDK1 | ACADVL | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| VNN2 | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| EEF2K | ACADVL | 18337751 24234451 25348397 | association | physical interaction,biochemical | ComPPI,IntAct |
| TRIM25 | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| IL31RA | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| ECSIT | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| CKAP5 | ACADVL | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ATF2 | ACADVL | 22304920 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| IFI16 | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| EIF4A3 | ACADVL | 18337751 24234451 25348397 | association | biochemical | ComPPI,IntAct |
| NDUFA13 | ACADVL | 25348397 | N/A | physical interaction | ComPPI |
| HSPD1 | ACADVL | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| RPSA | ACADVL | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| ACADVL | ATP5MG | 25348397 | N/A | physical interaction | ComPPI |
| ACADVL | SURF1 | 25348397 | N/A | physical interaction | ComPPI |
| ACADVL | MRM1 | 25348397 | N/A | physical interaction | ComPPI |
| ACADVL | KIF2A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ACADVL | NDUFA4 | 25348397 | N/A | physical interaction | ComPPI |
| ACADVL | SINHCAF | 25348397 | N/A | physical interaction | ComPPI |
| ACADVL | ALB | 18337751 24234451 25348397 | association | biochemical | ComPPI,IntAct |
| ACADVL | CDK1 | 18337751 24234451 25348397 | association | biochemical | ComPPI,IntAct |
| ACADVL | SIRT4 | 24234451 25348397 25525879 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ACADVL | COX6B1 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
