GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
HSH2D |
FullNmae |
hematopoietic SH2 domain containing |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:24920 |
EnsembleID |
ENSG00000196684 |
Uniprot |
Q96JZ2 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
HSH2D |
mpt |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
HSH2D |
GO:0002903,GO:0005515,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0007165,GO:0030674,GO:0042110,GO:0051902 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
HSH2D |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
ETS1 |
HSH2D |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
YBX1 |
HSH2D |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
TFAP2C |
HSH2D |
20629094
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
HSH2D |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
HSH2D |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
HSH2D |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
HSH2D |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
HSH2D |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000237AF9 |
HSH2D |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CRK |
HSH2D |
25348397
|
N/A |
two hybrid,physical interaction |
ComPPI |
KIT |
HSH2D |
24234451
24728074
25348397
|
N/A |
fluorescence polarization spectroscopy |
ComPPI,IntAct |
AR |
HSH2D |
24234451
24728074
25348397
|
N/A |
fluorescence polarization spectroscopy |
ComPPI,IntAct |
FES |
HSH2D |
11700021
14525934
25348397
|
N/A |
two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid |
ComPPI,HPRD |
GAB1 |
HSH2D |
24234451
24728074
25348397
|
N/A |
fluorescence polarization spectroscopy |
ComPPI,IntAct |
PIK3R3 |
HSH2D |
24234451
25348397
25814554
|
physical association |
two hybrid,physical interaction,two hybrid array,validated two hybrid |
ComPPI,IntAct |
MET |
HSH2D |
24234451
24728074
25348397
|
N/A |
fluorescence polarization spectroscopy |
ComPPI,IntAct |
HSH2D |
TNK2 |
11700021
14525934
24234451
25348397
25814554
|
physical association |
two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid |
ComPPI,HPRD,IntAct |
HSH2D |
MPP3 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
HSH2D |
PINK1 |
24234451
25348397
25814554
|
physical association |
two hybrid,physical interaction,two hybrid array,validated two hybrid |
ComPPI,IntAct |
HSH2D |
TSC1 |
24234451
25348397
25814554
|
physical association |
two hybrid,physical interaction,two hybrid array,validated two hybrid |
ComPPI,IntAct |
Visualization