Gene Information gene info

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GENE：MYOC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYOC
FullNmae myocilin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7610
EnsembleID ENSG00000034971
Uniprot Q99972

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYOC mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYOC GO:0001649,GO:0001649,GO:0001953,GO:0001968,GO:0005109,GO:0005515,GO:0005615,GO:0005615,GO:0005741,GO:0005743,GO:0005758,GO:0005783,GO:0005791,GO:0005794,GO:0005794,GO:0005929,GO:0007165,GO:0014734,GO:0022011,GO:0030335,GO:0030971,GO:0031175,GO:0031410,GO:0032027,GO:0033268,GO:0035024,GO:0038031,GO:0038133,GO:0043408,GO:0045162,GO:0046872,GO:0051496,GO:0051497,GO:0051894,GO:0051897,GO:0051901,GO:0060348,GO:0062023,GO:0070062,GO:1900026

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 MYOC 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 MYOC 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF MYOC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MYOC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MYOC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
USF1 MYOC N/A trascriptional regulation,stimulation inferred by curator TFlink
USF2 MYOC N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029D9F1 MYOC 21282569 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
LGALS3 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FTL MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SGTA MYOC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COL1A2 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
VIM MYOC 25348397 N/A physical interaction ComPPI
ACTG1 MYOC 25348397 N/A physical interaction ComPPI
ACTB MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SERPINF1 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ITGA7 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CD81 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
GAPDH MYOC 14525934 16289162 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
ENO1 MYOC 14525934 16289162 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SPARC MYOC 20926826 24234451 25348397 physical association two hybrid,enzyme linked immunosorbent assay ComPPI,IntAct
SPARCL1 MYOC 20926826 24234451 25348397 physical association two hybrid,enzyme linked immunosorbent assay ComPPI,IntAct
TNFRSF1A MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
EEF1A1 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PKM MYOC 25348397 N/A physical interaction ComPPI
TIMP1 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ANXA2 MYOC 14525934 16289162 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HSPA4 MYOC 25348397 N/A physical interaction ComPPI
FUBP1 MYOC 25348397 N/A two hybrid,physical interaction ComPPI
FBN1 MYOC 11923248 25348397 27898060 N/A physical interaction,in vitro ComPPI,OmniPath
CLIC1 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
COL3A1 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NOTCH2 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
LAMA5 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ECE1 MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC OLFM3 12019210 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
MYOC ACTA2 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC A2M 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC HAGH 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC GGTLC1 25348397 N/A two hybrid ComPPI
MYOC OLFML3 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC PKLR 14525934 16289162 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
MYOC RFC1 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC IGLL1 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC MAEA 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC C1QB 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC TKT 14525934 16289162 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MYOC CAP1 14525934 16289162 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MYOC ALDOA 14525934 16289162 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MYOC MYL2 11773029 14525934 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,electron microscopy,experimental interaction detection,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
MYOC FN1 11773026 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MYOC TGFBR1 14525934 16289162 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
MYOC EEF1A1P5 25348397 N/A physical interaction ComPPI
MYOC MYH11 25348397 N/A physical interaction ComPPI
MYOC TPM1 25348397 N/A physical interaction ComPPI
MYOC ANXA2P2 25348397 N/A physical interaction ComPPI
CKM MYOC 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MYOC MYOC 11527946 11773029 14525934 24234451 physical association two hybrid,experimental interaction detection HPRD,IntAct
MYOC FZD3 19188438 27898060 N/A N/A OmniPath
MYOC FZD7 19188438 27898060 N/A N/A OmniPath
MYOC FZD1 19188438 27898060 N/A N/A OmniPath
MYOC FZD4 19188438 27898060 N/A N/A OmniPath
MYOC FZD10 19188438 27898060 N/A N/A OmniPath

Visualization










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