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GENE：PICALM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PICALM
FullNmae phosphatidylinositol binding clathrin assembly protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15514
EnsembleID ENSG00000073921
Uniprot Q13492

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PICALM mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PICALM immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PICALM ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PICALM GO:0000149,GO:0000149,GO:0001540,GO:0005515,GO:0005545,GO:0005545,GO:0005546,GO:0005546,GO:0005634,GO:0005769,GO:0005794,GO:0005829,GO:0005886,GO:0005905,GO:0005905,GO:0005905,GO:0006879,GO:0006897,GO:0006898,GO:0006900,GO:0007409,GO:0007611,GO:0008021,GO:0009986,GO:0010629,GO:0016020,GO:0016020,GO:0016185,GO:0016188,GO:0016192,GO:0016197,GO:0030097,GO:0030100,GO:0030132,GO:0030136,GO:0030136,GO:0030276,GO:0031267,GO:0031623,GO:0031982,GO:0032050,GO:0032050,GO:0032880,GO:0035459,GO:0042734,GO:0043025,GO:0043231,GO:0043547,GO:0045211,GO:0045296,GO:0045334,GO:0045893,GO:0048156,GO:0048261,GO:0048268,GO:0048268,GO:0048471,GO:0048813,GO:0050750,GO:0060586,GO:0065003,GO:0070381,GO:0072583,GO:0072583,GO:0097418,GO:0097494,GO:0097753,GO:0098894,GO:0150093,GO:0150093,GO:1902004,GO:1902959,GO:1902961,GO:1902963,GO:1903077,GO:2000009

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 PICALM 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 PICALM 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PICALM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PICALM 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PICALM 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PICALM 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PICALM 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PICALM 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PICALM 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PICALM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PICALM N/A 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 PICALM 18668040 20584899 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS0000122ED0 PICALM 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 PICALM 18668040 21572407 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000045B99E PICALM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 PICALM 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PICALM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 PICALM 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F PICALM 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 PICALM 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 PICALM 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD PICALM 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 PICALM 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 PICALM 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L PICALM 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RALBP1 PICALM 25348397 N/A physical interaction ComPPI
MCM2 PICALM 25348397 N/A physical interaction ComPPI
DAB2 PICALM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CASP3 PICALM 10926122 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FHL2 PICALM 22829078 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,confocal microscopy ComPPI,IntAct
ITGB1 PICALM 25348397 N/A physical interaction ComPPI
PFKM PICALM 25348397 N/A physical interaction ComPPI
NTRK1 PICALM 25348397 N/A physical interaction ComPPI
PICALM AP2A1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PICALM CLTCL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI,IntAct
PICALM CASP8 10926122 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PICALM EHD2 14525934 15182197 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PICALM CLTC 10436022 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PICALM DDIT3 14525934 1547942 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PICALM PLCG1 10926122 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PICALM ITSN1 25348397 N/A physical interaction ComPPI
PICALM HIP1R 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM LAMTOR3 25348397 N/A physical interaction ComPPI
PICALM EEF1A1 25348397 N/A physical interaction ComPPI
PICALM DNM2 25348397 N/A physical interaction ComPPI
PICALM EGFR 25348397 N/A physical interaction ComPPI
PICALM FLOT1 25348397 N/A physical interaction ComPPI
PICALM ILF3 25348397 N/A physical interaction ComPPI
PICALM HNRNPDL 25348397 N/A physical interaction ComPPI
PICALM SH3GLB2 25348397 N/A physical interaction ComPPI
PICALM ABCC2 25348397 N/A physical interaction ComPPI
PICALM CD55 25348397 N/A physical interaction ComPPI
PICALM SIRT1 25348397 N/A physical interaction ComPPI
PICALM FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PICALM VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PICALM ITGA4 25348397 N/A physical interaction ComPPI
PICALM PELI2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PICALM ITLN1 25348397 N/A physical interaction ComPPI
PICALM PIMREG 25348397 N/A physical interaction ComPPI
PICALM CYP1A1 25348397 N/A physical interaction ComPPI
PICALM HNRNPA1 25348397 N/A physical interaction ComPPI
PICALM HNRNPD 25348397 N/A physical interaction ComPPI
PICALM LPP 25348397 N/A physical interaction ComPPI
PICALM DDX1 25348397 N/A physical interaction ComPPI
PICALM EWSR1 25348397 N/A physical interaction ComPPI
PICALM FERMT2 25348397 N/A physical interaction ComPPI
PICALM FUS 25348397 N/A physical interaction ComPPI
PICALM ILK 25348397 N/A physical interaction ComPPI
PICALM NPLOC4 25348397 N/A physical interaction ComPPI
PICALM PTPRF 25348397 N/A physical interaction ComPPI
PICALM VCL 25348397 N/A physical interaction ComPPI
PICALM PXN 25348397 N/A physical interaction ComPPI
PICALM STXBP1 25348397 N/A physical interaction ComPPI
PICALM TRIM25 25348397 N/A physical interaction ComPPI
PICALM UNC13D 25348397 N/A physical interaction ComPPI
PICALM XPO1 25348397 N/A physical interaction ComPPI
PICALM AP2B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM AP2M1 25348397 N/A physical interaction ComPPI
PICALM CLTA 25348397 N/A physical interaction ComPPI
PICALM CLTB 25348397 N/A physical interaction ComPPI
PICALM EPS15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM MYO6 25348397 N/A physical interaction ComPPI
PICALM PIK3C2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM SEC13 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM CAPZA2 25348397 N/A physical interaction ComPPI
PICALM DBN1 25348397 N/A physical interaction ComPPI
PICALM MYH9 25348397 N/A physical interaction ComPPI
PICALM LIMA1 25348397 N/A physical interaction ComPPI
PICALM GTSE1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM CLINT1 25348397 N/A physical interaction ComPPI
PICALM SEC16A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM BMP2K 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM WNK1 25348397 N/A physical interaction ComPPI
PICALM PRRC2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM STON2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM FCHO2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PICALM SMURF1 25348397 N/A physical interaction ComPPI
PICALM CDH1 25348397 N/A physical interaction ComPPI
PICALM STAMBPL1 25348397 N/A physical interaction ComPPI
PICALM DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PICALM YBX1 23986595 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PICALM OCRL 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PICALM TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SOX2 PICALM 25348397 N/A physical interaction ComPPI
ILVBL PICALM 25348397 N/A physical interaction ComPPI
SNRNP27 PICALM 25348397 N/A physical interaction ComPPI
MKI67 PICALM 24234451 26949251 association anti tag coimmunoprecipitation IntAct
PICALM CLTC 10436022 16491119 26496610 27898060 stimulant N/A OmniPath
PICALM CLTCL1 10436022 16491119 27898060 stimulant N/A OmniPath
PIMREG PICALM 16491119 27898060 inhibition N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BDFD3 PICALM 27087310 direct interaction,inhibition N/A NPInter

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