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GENE：ACP5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACP5
FullNmae acid phosphatase 5, tartrate resistant
LocusType gene with protein product
Status Approved
HGNC_id HGNC:124
EnsembleID ENSG00000102575
Uniprot P13686

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACP5 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
ACP5 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
ACP5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACP5 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ACP5 GO:0003993,GO:0005764,GO:0005829,GO:0006809,GO:0008198,GO:0008198,GO:0008199,GO:0008199,GO:0010936,GO:0016020,GO:0016311,GO:0032496,GO:0032691,GO:0032695,GO:0032720,GO:0032929,GO:0034097,GO:0042554,GO:0045019,GO:0045453,GO:0050728,GO:0050830,GO:0060349

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACP5 hsa:54 path:hsa00740 Riboflavin metabolism - Homo sapiens (human)
ACP5 hsa:54 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ACP5 hsa:54 path:hsa04142 Lysosome - Homo sapiens (human)
ACP5 hsa:54 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
ACP5 hsa:54 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 ACP5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ACP5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC ACP5 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ACP5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ACP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ACP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ACP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ACP5 11481336 15737031 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ACP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ACP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ACP5 11481336 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 ACP5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
MAPK9 ACP5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACP5 SPP1 14525934 25348397 27898060 2808373 8195113 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
ACP5 GPC4 12009023 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
ACP5 EGR2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACP5 RPA2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACP5 TNFSF10 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACP5 PDCD5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACP5 SNRNP40 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACP5 ZBTB16 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ACP5 PPP2CB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ACP5 HSPA5 25348397 N/A physical interaction ComPPI
ACP5 KLHL15 25348397 N/A physical interaction ComPPI
ACP5 CIZ1 25348397 N/A physical interaction ComPPI
ACP5 CALR 25348397 N/A physical interaction ComPPI
ACP5 CLGN 25348397 N/A physical interaction ComPPI
ACP5 OS9 25348397 N/A physical interaction ComPPI
ACP5 PDIA3 25348397 N/A physical interaction ComPPI
ACP5 CANX 25348397 N/A physical interaction ComPPI
ACP5 SEL1L 25348397 N/A physical interaction ComPPI
ACP5 P4HB 25348397 N/A physical interaction ComPPI
ACP5 GANAB 25348397 N/A physical interaction ComPPI
ACP5 NGLY1 25348397 N/A physical interaction ComPPI
ACP5 ARSA 27898060 8706666 N/A N/A OmniPath

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