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GENE：ANGPTL4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ANGPTL4
FullNmae angiopoietin like 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16039
EnsembleID ENSG00000167772
Uniprot Q9BY76

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ANGPTL4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ANGPTL4 GO:0001525,GO:0001666,GO:0004857,GO:0004857,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005615,GO:0006629,GO:0042802,GO:0043066,GO:0043335,GO:0045766,GO:0051005,GO:0062023,GO:0070328,GO:0070328,GO:0072562,GO:0072577,GO:2000352

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ANGPTL4 hsa:51129 path:hsa03320 PPAR signaling pathway - Homo sapiens (human)
ANGPTL4 hsa:51129 path:hsa04979 Cholesterol metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CEBPD ANGPTL4 23180781 25889814 physical association anti tag coimmunoprecipitation InnateDB
HIF1A ANGPTL4 23180781 25889814 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ANGPTL4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 ANGPTL4 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ANGPTL4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ANGPTL4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A ANGPTL4 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 ANGPTL4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF ANGPTL4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ANGPTL4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ANGPTL4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ANGPTL4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PPARA ANGPTL4 12099716 15190076 trascriptional regulation,stimulation inferred by curator TFlink
PPARD ANGPTL4 15190076 trascriptional regulation,stimulation inferred by curator TFlink
PPARG ANGPTL4 14570927 15190076 trascriptional regulation,stimulation inferred by curator TFlink
SMAD3 ANGPTL4 24330518 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 ANGPTL4 N/A trascriptional regulation,stimulation inferred by curator TFlink
ESR2 ANGPTL4 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARA ANGPTL4 N/A trascriptional regulation,stimulation inferred by curator TFlink
STAT5B ANGPTL4 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000272A92 ANGPTL4 25416803 26546816 mrna cleavage,inhibition experimental interaction detection,western blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDKN2C ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ITGB5 ANGPTL4 21397862 24234451 25348397 association,physical association anti bait coimmunoprecipitation,surface plasmon resonance,proximity ligation assay ComPPI,IntAct
ACTB ANGPTL4 25348397 N/A physical interaction ComPPI
BRMS1 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAC1 ANGPTL4 21397862 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
FBXW7 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ITGB1 ANGPTL4 21397862 24234451 25348397 physical association surface plasmon resonance,proximity ligation assay,surface plasmon resonance array ComPPI,IntAct
CDKN2A ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SMARCA4 ANGPTL4 25348397 N/A physical interaction ComPPI
CASP8 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MYC ANGPTL4 25348397 N/A physical interaction ComPPI
LPL ANGPTL4 19318355 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
AURKA ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ESR1 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NMT1 ANGPTL4 25348397 N/A physical interaction ComPPI
ITIH2 ANGPTL4 25348397 N/A physical interaction ComPPI
KAT5 ANGPTL4 25348397 N/A physical interaction ComPPI
AASDHPPT ANGPTL4 25348397 N/A physical interaction ComPPI
DNAJB4 ANGPTL4 25348397 N/A physical interaction ComPPI
WDR47 ANGPTL4 25348397 N/A physical interaction ComPPI
NMT2 ANGPTL4 25348397 N/A physical interaction ComPPI
ANGPTL4 CDKN2A 25348397 N/A physical interaction ComPPI
ANGPTL4 PM20D2 25348397 N/A physical interaction ComPPI
ANGPTL4 ARMC8 25348397 N/A physical interaction ComPPI
ANGPTL4 PTK2 21397862 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ANGPTL4 ANGPTL4 19028676 24234451 N/A molecular sieving IntAct
FLOT2 ANGPTL4 10911987 11604499 12654312 15610740 17395615 18212056 27898060 N/A N/A OmniPath

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