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GENE：AOX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AOX1
FullNmae aldehyde oxidase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:553
EnsembleID ENSG00000138356
Uniprot Q06278

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AOX1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AOX1 GO:0004031,GO:0004031,GO:0005506,GO:0005829,GO:0005829,GO:0006629,GO:0006805,GO:0042802,GO:0042803,GO:0043546,GO:0050660,GO:0051287,GO:0051537,GO:0070062,GO:0071949

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AOX1 hsa:316 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
AOX1 hsa:316 path:hsa00350 Tyrosine metabolism - Homo sapiens (human)
AOX1 hsa:316 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
AOX1 hsa:316 path:hsa00750 Vitamin B6 metabolism - Homo sapiens (human)
AOX1 hsa:316 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
AOX1 hsa:316 path:hsa00830 Retinol metabolism - Homo sapiens (human)
AOX1 hsa:316 path:hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human)
AOX1 hsa:316 path:hsa01100 Metabolic pathways - Homo sapiens (human)
AOX1 hsa:316 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR AOX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
HIF1A AOX1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 AOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 AOX1 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP3 AOX1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 AOX1 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
ERRFI1 AOX1 25348397 N/A physical interaction ComPPI
CRKL AOX1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RCHY1 AOX1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ABCA1 AOX1 12054535 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RBL1 AOX1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AOX1 GK 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct

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