Gene Information gene info

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GENE：ASL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ASL
FullNmae argininosuccinate lyase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:746
EnsembleID ENSG00000126522
Uniprot P04424

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ASL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ASL GO:0000050,GO:0004056,GO:0004056,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0006525,GO:0006526,GO:0007626,GO:0009791,GO:0019676,GO:0042450,GO:0042802,GO:0045429,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ASL hsa:435 path:hsa00220 Arginine biosynthesis - Homo sapiens (human)
ASL hsa:435 path:hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human)
ASL hsa:435 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ASL hsa:435 path:hsa01230 Biosynthesis of amino acids - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
POLR3G ASL 19631370 23180781 physical association tandem affinity purification InnateDB
ASL NTAQ1 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 ASL 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA ASL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ASL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ASL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ASL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ASL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ASL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ASL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
FBP1 ASL 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BAG3 ASL 25348397 N/A physical interaction ComPPI
TUFM ASL 25348397 N/A physical interaction ComPPI
HMOX1 ASL 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CLK1 ASL 25348397 N/A physical interaction ComPPI
PDHA1 ASL 25348397 N/A physical interaction ComPPI
GDI1 ASL 25348397 N/A physical interaction ComPPI
QARS1 ASL 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NEDD8 ASL 25348397 N/A physical interaction ComPPI
CSNK2A2 ASL 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
OVGP1 ASL 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRPK2 ASL 25348397 N/A physical interaction ComPPI
TRIM3 ASL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NCDN ASL 25348397 N/A physical interaction ComPPI
ASL GINS4 25348397 N/A physical interaction ComPPI
ASL HK1 25348397 N/A physical interaction ComPPI
ASL NTAQ1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ASL ASL 11747432 14525934 21988832 24234451 25416956 9256435 physical association two hybrid,experimental interaction detection,two hybrid array,two hybrid prey pooling approach HPRD,IntAct

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