Gene Information gene info

GENE:C8G

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C8G
FullNmae complement C8 gamma chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1354
EnsembleID ENSG00000176919
Uniprot P07360

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C8G immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C8G GO:0001848,GO:0005515,GO:0005576,GO:0005579,GO:0005886,GO:0006957,GO:0006958,GO:0019841,GO:0031640,GO:0044877,GO:0050778,GO:0070062,GO:0072562

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C8G hsa:733 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C8G hsa:733 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
C8G hsa:733 path:hsa05020 Prion disease - Homo sapiens (human)
C8G hsa:733 path:hsa05146 Amoebiasis - Homo sapiens (human)
C8G hsa:733 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C8G hsa:733 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 C8G 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 C8G 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF C8G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 C8G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A C8G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 C8G N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 C8G 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
UBQLN2 C8G 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GL1 C8G 25348397 N/A physical interaction ComPPI
SEC24B C8G 25348397 N/A physical interaction ComPPI
C8G CEMIP2 25348397 N/A physical interaction ComPPI

Visualization