Gene Information gene info

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GENE：CAT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CAT
FullNmae catalase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1516
EnsembleID ENSG00000121691
Uniprot P04040

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CAT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CAT cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CAT GO:0000302,GO:0001649,GO:0001657,GO:0001666,GO:0004046,GO:0004096,GO:0004096,GO:0005576,GO:0005737,GO:0005739,GO:0005777,GO:0005777,GO:0005778,GO:0005782,GO:0005829,GO:0005925,GO:0006641,GO:0008203,GO:0009060,GO:0009410,GO:0009642,GO:0009650,GO:0010193,GO:0010288,GO:0014823,GO:0014854,GO:0016020,GO:0016209,GO:0016684,GO:0019899,GO:0020027,GO:0020037,GO:0020037,GO:0032355,GO:0032868,GO:0032991,GO:0033189,GO:0033197,GO:0033591,GO:0034774,GO:0042542,GO:0042744,GO:0042744,GO:0042802,GO:0042803,GO:0043066,GO:0043231,GO:0045471,GO:0046686,GO:0046872,GO:0050661,GO:0051781,GO:0055093,GO:0061692,GO:0062151,GO:0070062,GO:0070542,GO:0071363,GO:0080184,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CAT hsa:847 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
CAT hsa:847 path:hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)
CAT hsa:847 path:hsa01100 Metabolic pathways - Homo sapiens (human)
CAT hsa:847 path:hsa01200 Carbon metabolism - Homo sapiens (human)
CAT hsa:847 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
CAT hsa:847 path:hsa04146 Peroxisome - Homo sapiens (human)
CAT hsa:847 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
CAT hsa:847 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
CAT hsa:847 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
CAT hsa:847 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
CAT hsa:847 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TLR10 CAT 16482509 23180781 physical association two hybrid InnateDB
CAT GRB2 15182856 23180781 physical association anti tag coimmunoprecipitation,far western blotting InnateDB
APP CAT 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CAT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CAT 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CAT 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 CAT 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CAT 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CAT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR3 CAT 1906159 trascriptional regulation,stimulation inferred by curator TFlink
ETV1 CAT 19763505 trascriptional regulation,stimulation inferred by curator TFlink
NFE2L2 CAT 22493435 trascriptional regulation,stimulation inferred by curator TFlink
PPARD CAT 18048767 trascriptional regulation,stimulation inferred by curator TFlink
PPARG CAT 20075562 trascriptional regulation,stimulation inferred by curator TFlink
SP1 CAT 11479230 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 CAT 11479230 trascriptional regulation,stimulation inferred by curator TFlink
WT1 CAT N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002152A8 CAT 22880027 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002152A8 CAT 22880027 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 CAT 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 CAT 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
PRKCD CAT 22135298 phosphorylation N/A PhosphoSite
ABL1 CAT 22135298 phosphorylation N/A PhosphoSite
ABL2 CAT 22135298 phosphorylation N/A PhosphoSite
CAT CAT 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RAB14 CAT 23333653 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
LDHB CAT 25348397 N/A physical interaction ComPPI
LDHA CAT 25348397 N/A physical interaction ComPPI
CFL1 CAT 25348397 N/A physical interaction ComPPI
KEAP1 CAT 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MCM2 CAT 25348397 N/A physical interaction ComPPI
CYCS CAT 25348397 N/A physical interaction ComPPI
NUDT12 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ACOX3 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PTPN11 CAT 14525934 15556604 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct,OmniPath
ORC4 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
JUP CAT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACOX1 CAT 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PGM1 CAT 25348397 N/A physical interaction ComPPI
NTRK1 CAT 25348397 N/A physical interaction ComPPI
ENO1 CAT 25348397 N/A physical interaction ComPPI
SNX6 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SMARCA4 CAT 24234451 25348397 26496610 29568061 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PRDX1 CAT 25348397 N/A physical interaction ComPPI
CFTR CAT 25348397 N/A physical interaction ComPPI
RAB6A CAT 23333653 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
RPA2 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SCP2 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EHHADH CAT 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
POLD1 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MTA1 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ACTR3 CAT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MECP2 CAT 25348397 N/A physical interaction ComPPI
ZBTB33 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ACE2 CAT 25348397 N/A physical interaction ComPPI
PHYH CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NFKB1 CAT 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
HSPE1 CAT 25348397 N/A physical interaction ComPPI
PEX14 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PECR CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GNAS CAT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ESR1 CAT 25348397 N/A physical interaction ComPPI
ORC3 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SNX5 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CFL2 CAT 25348397 N/A physical interaction ComPPI
SOD1 CAT 25348397 N/A physical interaction ComPPI
AGPS CAT 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
GNPAT CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GNG12 CAT 24234451 25348397 29568061 association pull down ComPPI,IntAct
STIM1 CAT 25348397 N/A physical interaction ComPPI
ABL2 CAT 12777400 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CAT TLR10 14525934 16482509 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
CAT SUMO4 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CAT ABL1 25348397 N/A physical interaction ComPPI
CAT PEX5 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CAT APP 10567208 21832049 24234451 25348397 27898060 N/A physical interaction,enzyme linked immunosorbent assay ComPPI,IntAct,OmniPath
CAT HSD17B4 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CAT MOV10 25348397 N/A physical interaction ComPPI
CAT CCDC8 25348397 N/A physical interaction ComPPI
CAT ACAA1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CAT AGL 25348397 N/A physical interaction ComPPI
CAT ALDH7A1 25348397 N/A physical interaction ComPPI
CAT ATP5IF1 25348397 N/A physical interaction ComPPI
CAT BCAT2 25348397 N/A physical interaction ComPPI
CAT ENO3 25348397 N/A physical interaction ComPPI
CAT PPA2 25348397 N/A physical interaction ComPPI
CAT SOD2 25348397 N/A physical interaction ComPPI
CAT SORD 25348397 N/A physical interaction ComPPI
CAT UFC1 25348397 N/A physical interaction ComPPI
CAT FAHD1 25348397 N/A physical interaction ComPPI
CAT FAHD2A 25348397 N/A physical interaction ComPPI
CAT PRDX2 25348397 N/A physical interaction ComPPI
CAT PRDX5 25348397 N/A physical interaction ComPPI
CAT TANGO2 25348397 N/A physical interaction ComPPI
CAT GNAS 25348397 N/A physical interaction ComPPI
CAT GNAS 25348397 N/A physical interaction ComPPI
CAT CYLD 25348397 N/A physical interaction ComPPI
CAT GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CAT TYSND1 22002062 24234451 25348397 29568061 colocalization,association pull down,confocal microscopy,proximity-dependent biotin identification ComPPI,IntAct
CAT LACC1 24234451 25348397 27478939 colocalization,physical association confocal microscopy,proximity ligation assay ComPPI,IntAct
CAT GRPEL1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT DHX40 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT NUDT19 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CAT GSTK1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT CROT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT HACL1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT DECR2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT PNPLA8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT DHRS4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT ZADH2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT LONP2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CAT ACAD11 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT HSDL2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT HMGCL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT EPHX2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT G6PD 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT ECI2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT VWA8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT LIMA1 24234451 25348397 29568061 association pull down ComPPI,IntAct
CAT MLF2 24234451 25348397 29568061 association pull down ComPPI,IntAct
CAT POTEJ 24234451 25348397 29568061 association pull down ComPPI,IntAct
CAT MYO1B 24234451 25348397 29568061 association pull down ComPPI,IntAct
CAT TBC1D19 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT KIAA1841 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT NT5E 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT AHSG 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT NME2P1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT PSMD12 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT SCML2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT YEATS2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT C11ORF49 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT ZCCHC8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ECH1 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
USP53 CAT 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACOT8 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ISOC1 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAT BSK 25348397 N/A two hybrid ComPPI
CAT TAK1 25348397 N/A physical interaction ComPPI
CAT CAT 10656833 10666617 11134921 14525934 21988832 24234451 29568061 association,physical association two hybrid,experimental interaction detection,pull down,proximity-dependent biotin identification HPRD,IntAct
METTL14 CAT 24234451 29507755 association anti tag coimmunoprecipitation IntAct
DAG1 CAT 24234451 association cross-linking study IntAct
PRKCD CAT 24211614 27898060 N/A N/A OmniPath
ABL2 CAT 12777400 12950161 20841568 27898060 stimulant N/A OmniPath
CAT GRB2 15182856 27898060 N/A N/A OmniPath
ABL1 CAT 12777400 12950161 20841568 27898060 stimulant N/A OmniPath

Visualization










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