Gene Information gene info

  1. Home

GENE：CCN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CCN2
FullNmae cellular communication network factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2500
EnsembleID ENSG00000118523
Uniprot P29279

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CCN2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCN2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCN2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CCN2 GO:0001502,GO:0001503,GO:0001525,GO:0001894,GO:0002062,GO:0005178,GO:0005515,GO:0005520,GO:0005576,GO:0005794,GO:0005886,GO:0007155,GO:0007160,GO:0007165,GO:0007229,GO:0008201,GO:0008543,GO:0008544,GO:0009611,GO:0010629,GO:0016477,GO:0030324,GO:0031012,GO:0032330,GO:0035988,GO:0043231,GO:0045597,GO:0046330,GO:0051496,GO:0062023,GO:0070374,GO:0071897,GO:0072593

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CCN2 hsa:1490 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
CCN2 hsa:1490 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CCN2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA3 CCN2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CCN2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
RELA CCN2 20018891 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA CCN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CCN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CCN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CCN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CCN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CCN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 CCN2 16829517 trascriptional regulation,stimulation inferred by curator TFlink
FLI1 CCN2 16829517 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A CCN2 17034590 trascriptional regulation,stimulation inferred by curator TFlink
JUN CCN2 20711235 trascriptional regulation,stimulation inferred by curator TFlink
SP1 CCN2 12888575 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 CCN2 12888575 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 CCN2 21245987 trascriptional regulation,stimulation inferred by curator TFlink
WT1 CCN2 10973960 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004F4657 CCN2 23390502 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000035CC3E CCN2 16331254 19233176 rna interference,inhibition array technology,western blot,northern blot,miRNA interference luciferase reporter assay miRSponge
URS0000016914 CCN2 23056551 rna interference,inhibition western blot miRSponge
URS000035CC3E CCN2 16331254 19233176 25416803 27421245 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000016914 CCN2 23056551 25416803 mrna cleavage,inhibition western blot TarBase
URS00004F4657 CCN2 23390502 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000ED600 CCN2 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000A057E CCN2 23681229 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000032BD73 CCN2 24065814 25416803 25451078 26945106 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000427B68 CCN2 21572407 22012620 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004719AB CCN2 21572407 22012620 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000077AED CCN2 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 CCN2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 CCN2 21572407 22012620 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 CCN2 21572407 22012620 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000040EE1D CCN2 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000017EE98 CCN2 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000254A6 CCN2 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000008A99 CCN2 25416803 27075467 27398154 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000003ABC4 CCN2 25416803 28079129 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000003575B CCN2 25416803 27923814 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
TGFB1 CCN2 10457363 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ACTB CCN2 12470643 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ERBB4 CCN2 12297288 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CCN3 CCN2 14525934 25348397 9927660 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
VEGFA CCN2 11744618 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
CREBBP CCN2 25348397 N/A physical interaction ComPPI
EP300 CCN2 25348397 N/A physical interaction ComPPI
FGFR2 CCN2 23142580 24234451 25348397 N/A protein array ComPPI,IntAct
FZR1 CCN2 25348397 N/A physical interaction ComPPI
LRP1 CCN2 14525934 14585398 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CCN2 HSPG2 12811819 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CCN2 TGFB2 25348397 N/A in vivo ComPPI
CCN2 TGFB3 10457363 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CCN2 AP3D1 14525934 16457822 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CCN2 FBLN1 25348397 N/A physical interaction ComPPI
CCN2 ELAVL1 25348397 N/A physical interaction ComPPI
CCN2 EGFR 25348397 N/A physical interaction ComPPI
CCN2 TRIM68 25348397 N/A physical interaction ComPPI
CCN2 KLHL23 25348397 N/A physical interaction ComPPI
CCN2 LRP2 25348397 N/A physical interaction ComPPI
CCN2 ARIH1 25348397 N/A physical interaction ComPPI
CCN2 FN1 16457822 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,enzyme linked immunosorbent assay,imaging technique ComPPI,IntAct
CCN2 ITGA5 16457822 24234451 25348397 colocalization imaging technique ComPPI,IntAct
CCN2 FGFR3 23142580 24234451 25348397 N/A protein array ComPPI,IntAct
CCN2 ESR2 21629692 24234451 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down IntAct
CCN2 ESR1 21629692 24234451 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,enzyme linked immunosorbent assay,fluorescence microscopy IntAct
CCN2 NTRK1 15601748 27898060 N/A N/A OmniPath
CCN2 LRP6 18528331 27898060 stimulant N/A OmniPath
CCN2 ITGA5 16457822 18167060 27898060 N/A N/A OmniPath

Visualization










  Return