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GENE：CD27

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CD27
FullNmae CD27 molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11922
EnsembleID ENSG00000139193
Uniprot P26842

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CD27 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CD27 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CD27 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CD27 GO:0004888,GO:0005515,GO:0005576,GO:0005886,GO:0005886,GO:0007166,GO:0009897,GO:0016064,GO:0043027,GO:0043066,GO:0043066,GO:0045471,GO:0045579,GO:0045582,GO:0046330,GO:0070233,GO:0097191,GO:1901224

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CD27 hsa:939 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CD70 CD27 17237405 19062317 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
ETS1 CD27 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CD27 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CD27 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CD27 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CD27 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CD27 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CD27 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 CD27 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 CD27 25416803 28097098 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
CD27 TRAF3 25361965 interaction type N/A PTMCode2
TRAF3 CD27 25361965 interaction type N/A PTMCode2
CD27 CD5 25361965 interaction type N/A PTMCode2
CD5 CD27 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SCAMP1 CD27 25348397 N/A physical interaction ComPPI
HRAS CD27 25348397 N/A physical interaction ComPPI
CD59 CD27 25348397 N/A physical interaction ComPPI
CIB1 CD27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SEMG1 CD27 25348397 N/A physical interaction ComPPI
PROCR CD27 25348397 N/A physical interaction ComPPI
TRAF3 CD27 14525934 25348397 9582383 9794406 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SEMG2 CD27 25348397 N/A physical interaction ComPPI
UHRF2 CD27 21952639 24234451 25348397 physical association physical interaction,antibody array ComPPI,IntAct
ACTN2 CD27 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
GOLGA5 CD27 25348397 N/A physical interaction ComPPI
TRAF1 CD27 25348397 N/A physical interaction ComPPI
TRAF2 CD27 14525934 24234451 25348397 9582383 9692890 physical association two hybrid,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CD27 TRAF5 14525934 25348397 9582383 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CD27 SIVA1 14525934 16683188 24234451 25348397 27898060 9177220 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
CD27 CD70 14525934 15723067 25348397 7479974 8120384 8186199 8580829 9767422 9862673 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CD27 ELAVL1 25348397 N/A physical interaction ComPPI
CD27 C1GALT1 25348397 N/A physical interaction ComPPI
CD27 ATP2B3 25348397 N/A physical interaction ComPPI
CD27 COQ8B 25348397 N/A physical interaction ComPPI
CD27 BIRC2 25348397 N/A physical interaction ComPPI
CD27 CTNNA2 25348397 N/A physical interaction ComPPI
CD27 TCAF2 25348397 N/A physical interaction ComPPI
CD27 TTYH3 25348397 N/A physical interaction ComPPI
CD27 ADCY9 25348397 N/A physical interaction ComPPI
CD27 FAM241A 25348397 N/A physical interaction ComPPI
CD27 TMEM67 25348397 N/A physical interaction ComPPI
CD27 SLC25A51 25348397 N/A physical interaction ComPPI
CD27 SAAL1 25348397 N/A physical interaction ComPPI
CD27 SLC19A2 25348397 N/A physical interaction ComPPI
CD27 GNB2 25348397 N/A physical interaction ComPPI
CD27 TMEM214 25348397 N/A physical interaction ComPPI
CD27 CRELD1 25348397 N/A physical interaction ComPPI
CD70 CD27 12324477 15723067 21917027 26186194 26697006 27898060 7479974 8120384 8186199 8580829 9767422 9862673 stimulant N/A OmniPath

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