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GENE：CD38

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CD38
FullNmae CD38 molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1667
EnsembleID ENSG00000004468
Uniprot P28907

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CD38 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CD38 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CD38 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CD38 GO:0001666,GO:0003953,GO:0003953,GO:0005886,GO:0005886,GO:0005886,GO:0007165,GO:0007204,GO:0007565,GO:0009410,GO:0009986,GO:0010977,GO:0014824,GO:0016020,GO:0016323,GO:0016740,GO:0016849,GO:0019674,GO:0030307,GO:0030890,GO:0030890,GO:0032024,GO:0032355,GO:0032526,GO:0032570,GO:0033194,GO:0042100,GO:0042802,GO:0043066,GO:0045779,GO:0045892,GO:0045893,GO:0045907,GO:0050135,GO:0050853,GO:0060292,GO:0061809,GO:0070062,GO:0070555,GO:0097190

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CD38 hsa:952 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
CD38 hsa:952 path:hsa01100 Metabolic pathways - Homo sapiens (human)
CD38 hsa:952 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
CD38 hsa:952 path:hsa04640 Hematopoietic cell lineage - Homo sapiens (human)
CD38 hsa:952 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
CD38 hsa:952 path:hsa04970 Salivary secretion - Homo sapiens (human)
CD38 hsa:952 path:hsa04972 Pancreatic secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CD38 IRF1 17947510 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CD38 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CD38 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TCF3 CD38 21212793 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CD38 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CD38 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CD38 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CD38 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CD38 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CD38 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CD38 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CD38 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC CD38 11519042 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 CD38 17322278 18341691 18441094 trascriptional regulation,stimulation inferred by curator TFlink
RELA CD38 17322278 18341691 18441094 trascriptional regulation,stimulation inferred by curator TFlink
AR CD38 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARA CD38 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 CD38 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000821E0 CD38 22773691 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000054DF42 CD38 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C4762 CD38 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 CD38 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000013D17D CD38 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 CD38 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB CD38 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD CD38 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CD4 CD38 25361965 interaction type N/A PTMCode2
CD38 CD4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CD4 CD38 14525934 25348397 7539755 N/A experimental interaction detection,in vitro ComPPI,HPRD
CBL CD38 18974118 19635790 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PECAM1 CD38 25348397 N/A in vitro ComPPI
FCGR3A CD38 11895784 25348397 27898060 N/A physical interaction,in vitro ComPPI,OmniPath
CD38 LCK 10636863 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CD38 CD9 14525934 15941914 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CD38 CD3E 25348397 N/A physical interaction ComPPI
CD38 CD247 25348397 N/A physical interaction ComPPI
CD38 ZAP70 25348397 N/A physical interaction ComPPI
PRKG2 CD38 27898060 8663443 stimulant N/A OmniPath

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