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GENE：CD47

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CD47
FullNmae CD47 molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1682
EnsembleID ENSG00000196776
Uniprot Q08722

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CD47 immunogenic 36579538 Through literature reviews, a total of 108 ICD-related genes were identified (Supplement Table S1). retulator signature
CD47 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CD47 GO:0001525,GO:0005515,GO:0005886,GO:0006915,GO:0006954,GO:0007229,GO:0008284,GO:0009986,GO:0009986,GO:0009986,GO:0016477,GO:0022409,GO:0022409,GO:0032649,GO:0032653,GO:0032655,GO:0032675,GO:0032680,GO:0034113,GO:0035579,GO:0045428,GO:0050729,GO:0050766,GO:0050870,GO:0051496,GO:0070053,GO:0070053,GO:0070062,GO:0070821,GO:0071346,GO:0071347,GO:0071349,GO:0086080,GO:0098632,GO:1904669,GO:1905450,GO:2000439

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CD47 hsa:961 path:hsa04148 Efferocytosis - Homo sapiens (human)
CD47 hsa:961 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
THBS1 CD47 10657674 11509594 11982756 14568985 14996710 20150200015 22310103 22943793 26192618 8349738 association N/A ACSN
SIRPA CD47 16081415 17070842 23180781 physical association anti tag coimmunoprecipitation,solid phase assay InnateDB
CD14 CD47 11745332 23180781 physical association fluorescent resonance energy transfer InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CD47 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CD47 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CD47 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D CD47 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000017EA6A CD47 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F CD47 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 CD47 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 CD47 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 CD47 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 CD47 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA CD47 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 CD47 25416803 26506238 mrna cleavage,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay TarBase
URS00001E0AEA CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000045DBD CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000122F23 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000496C56 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000319E1 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000037B2E0 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C02E4 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000118224 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004283FE CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AEA5 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075B13F CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A25B CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000008AA34 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000038718E CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000260A3A CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000080D0A CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000001A7A CD47 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SIRPA CD47 25361965 interaction type N/A PTMCode2
CD47 SIRPA 25361965 interaction type N/A PTMCode2
ITGAV CD47 25361965 interaction type N/A PTMCode2
CD47 ITGAV 25361965 interaction type N/A PTMCode2
ITGB2 CD47 25361965 interaction type N/A PTMCode2
CD47 ITGB2 25361965 interaction type N/A PTMCode2
SIRPB1 CD47 25361965 interaction type N/A PTMCode2
CD47 SIRPB1 25361965 interaction type N/A PTMCode2
EPB42 CD47 25361965 interaction type N/A PTMCode2
CD47 EPB42 25361965 interaction type N/A PTMCode2
SIRPG CD47 25361965 interaction type N/A PTMCode2
CD47 SIRPG 25361965 interaction type N/A PTMCode2
THBS1 CD47 25361965 interaction type N/A PTMCode2
CD47 THBS1 25361965 interaction type N/A PTMCode2
CD47 BNIP3 25361965 interaction type N/A PTMCode2
BNIP3 CD47 25361965 interaction type N/A PTMCode2
CD47 ITGB1 25361965 interaction type N/A PTMCode2
ITGB1 CD47 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SET CD47 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
LGALS9C CD47 25348397 N/A physical interaction ComPPI
ITGB1 CD47 10397731 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ITGAV CD47 10545994 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GNAQ CD47 25348397 N/A physical interaction ComPPI
THBS1 CD47 10397731 14525934 25348397 8550562 9169439 N/A experimental interaction detection,in vivo ComPPI,HPRD
S1PR1 CD47 25348397 N/A physical interaction ComPPI
P2RY2 CD47 25348397 N/A in vivo ComPPI
LILRB4 CD47 25348397 N/A physical interaction ComPPI
SIRPA CD47 14525934 16291597 25348397 9872987 N/A experimental interaction detection,in vitro ComPPI,HPRD
EPB42 CD47 12176912 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CD47 RHAG 12393442 14525934 25348397 27898060 8563755 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CD47 BNIP3 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
CD47 UBQLN1 10549293 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
CD47 FAS 14525934 15917238 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CD47 GNAI1 11306274 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CD47 ELAVL1 25348397 N/A physical interaction ComPPI
CD47 SYNE4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CD47 TSPAN5 25348397 N/A physical interaction ComPPI
CD47 LGALS8 25348397 N/A physical interaction ComPPI
CD47 LGALS9 25348397 N/A physical interaction ComPPI
CD47 BSCL2 25348397 N/A physical interaction ComPPI
CD47 LPAR1 25348397 N/A physical interaction ComPPI
CD47 RETREG3 25348397 N/A physical interaction ComPPI
CD47 GNB3 25348397 N/A physical interaction ComPPI
CD47 GNAS 25348397 N/A physical interaction ComPPI
CD47 GNAS 25348397 N/A physical interaction ComPPI
CD47 GNAS 25348397 N/A physical interaction ComPPI
CD47 KLRG2 25348397 N/A physical interaction ComPPI
CD47 TM4SF18 25348397 N/A physical interaction ComPPI
CD47 TMEM128 25348397 N/A physical interaction ComPPI
CD47 SLC1A5 25348397 N/A physical interaction ComPPI
CD47 IPPK 25348397 N/A physical interaction ComPPI
CD47 WASF3 25348397 N/A physical interaction ComPPI
CD47 SIRPG 15383453 24234451 25348397 27898060 physical association fluorescence-activated cell sorting ComPPI,IntAct,OmniPath
CD47 ATP2B4 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
CD47 AQP1 23219802 24234451 25348397 association cross-linking study ComPPI,IntAct
CD47 ITGA2 10397731 24234451 association anti bait coimmunoprecipitation IntAct
THBS1 CD47 10397731 11980922 27898060 8550562 9169439 stimulant N/A OmniPath
CD14 CD47 11745332 27898060 N/A N/A OmniPath
THBS2 CD47 27898060 8550562 stimulant N/A OmniPath
COL4A3 CD47 10493512 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BC2C6 CD47 27087310 direct interaction,inhibition N/A NPInter

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