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GENE：CD48

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CD48
FullNmae CD48 molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1683
EnsembleID ENSG00000117091
Uniprot P09326

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CD48 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CD48 GO:0005515,GO:0005886,GO:0006952,GO:0016020,GO:0045121,GO:0070062,GO:0098552

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CD48 hsa:962 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CD48 CD2 10359122 15998796 16081768 19398758 19494291 26192618 26794910 interaction type N/A ACSN
CD48 SH2D1A 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
CD48 LAT 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
CD48 LCP2 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
CD48 PLCG1 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
CD48 CBL 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
CLEC2D CD48 16339513 18159636 20435894 22378844 24227772 26192618 8478617 9603467 interaction type N/A ACSN
KLRB1 CD48 16339513 18159636 20435894 22378844 24227772 26192618 8478617 9603467 interaction type N/A ACSN
HLA-C CD48 11513144 12515815 12917349 16606694 18835194 26192618 9751747 interaction type N/A ACSN
KIR2DL1 CD48 11513144 12515815 12917349 16606694 18835194 26192618 9751747 interaction type N/A ACSN
FCER1G CD48 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
HLA-G CD48 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
KIR2DL4 CD48 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
FLOT1 CD48 17634952 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CD48 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CD48 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CD48 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CD48 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CD48 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
LCK CD48 25361965 interaction type N/A PTMCode2
CD48 LCK 25361965 interaction type N/A PTMCode2
CD247 CD48 25361965 interaction type N/A PTMCode2
CD48 CD247 25361965 interaction type N/A PTMCode2
CD48 FYN 25361965 interaction type N/A PTMCode2
FYN CD48 25361965 interaction type N/A PTMCode2
CD48 CD2 25361965 interaction type N/A PTMCode2
CD2 CD48 25361965 interaction type N/A PTMCode2
IL18RAP CD48 25361965 interaction type N/A PTMCode2
CD48 IL18RAP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GNAI3 CD48 14525934 25348397 8650218 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK CD48 12007789 14525934 25348397 8104794 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CD2 CD48 12356317 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
CD247 CD48 14525934 16049493 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SQSTM1 CD48 25348397 N/A physical interaction ComPPI
FYN CD48 14525934 25348397 8104794 N/A experimental interaction detection,in vitro ComPPI,HPRD
CD48 CD244 11163399 14525934 15153464 16002700 18296487 24234451 25348397 9834056 physical association experimental interaction detection,fluorescence-activated cell sorting,in vitro,in vivo,solid phase assay ComPPI,HPRD,IntAct
CD48 IL18RAP 14525934 15760905 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CD48 IL18R1 14525934 15760905 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CD48 BRIX1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CD48 PRAP1 25348397 N/A physical interaction ComPPI
EEF1D CD48 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CD48 CD48 16002700 24234451 physical association comigration in non denaturing gel electrophoresis IntAct

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