Gene Information gene info

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GENE：CGA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CGA
FullNmae glycoprotein hormones, alpha polypeptide
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1885
EnsembleID ENSG00000135346
Uniprot P01215

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CGA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CGA GO:0005179,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005796,GO:0006590,GO:0007186,GO:0008284,GO:0009755,GO:0010469,GO:0010893,GO:0010893,GO:0016913,GO:0016913,GO:0016914,GO:0016914,GO:0016914,GO:0030335,GO:0030878,GO:0032275,GO:0035265,GO:0042699,GO:0045944,GO:0046621,GO:0046884,GO:0061696,GO:0061696

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CGA hsa:1081 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
CGA hsa:1081 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
CGA hsa:1081 path:hsa04912 GnRH signaling pathway - Homo sapiens (human)
CGA hsa:1081 path:hsa04913 Ovarian steroidogenesis - Homo sapiens (human)
CGA hsa:1081 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)
CGA hsa:1081 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)
CGA hsa:1081 path:hsa04923 Regulation of lipolysis in adipocytes - Homo sapiens (human)
CGA hsa:1081 path:hsa04929 GnRH secretion - Homo sapiens (human)
CGA hsa:1081 path:hsa05320 Autoimmune thyroid disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 CGA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
THRA CGA 9709914 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
THRB CGA 2480596 9709914 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 CGA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 CGA 10341006 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 CGA 10341006 trascriptional regulation,stimulation inferred by curator TFlink
DLX3 CGA 22446105 trascriptional regulation,stimulation inferred by curator TFlink
ETS2 CGA 15637148 trascriptional regulation,stimulation inferred by curator TFlink
MSX1 CGA 18379900 trascriptional regulation,stimulation inferred by curator TFlink
NANOG CGA 15983365 trascriptional regulation,stimulation inferred by curator TFlink
POU1F1 CGA 11081207 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A CGA 10648798 trascriptional regulation,stimulation inferred by curator TFlink
ATF2 CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
ATF4 CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
ESR1 CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
FOS CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
JUN CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
NFIC CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
PGR CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
TP53 CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
USF1 CGA N/A trascriptional regulation,stimulation inferred by curator TFlink
USF2 CGA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 CGA 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
LHCGR CGA 25361965 interaction type N/A PTMCode2
CGA LHCGR 25361965 interaction type N/A PTMCode2
CGA FSHR 25361965 interaction type N/A PTMCode2
FSHR CGA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PTPN12 CGA 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FSHR CGA 25348397 N/A physical interaction ComPPI
TSHB CGA 14525934 25348397 27898060 3839756 5002675 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
LHCGR CGA 10342833 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CGA CGB3 10373373 10563789 11266609 14525934 172504 25348397 2536708 2611225 2708337 7922031 8202136 9578495 N/A experimental interaction detection,x-ray crystallography,physical interaction,in vitro ComPPI,HPRD
CGA FSHB 10563789 11222739 14525934 15662415 22802634 24234451 25348397 27898060 physical association experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
CGA LHB 14525934 25348397 27898060 7679977 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
CGA PTN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CGA CGB1 25348397 N/A physical interaction ComPPI
CGA CGB2 25348397 N/A physical interaction ComPPI
CGA CGA 11222739 14525934 N/A experimental interaction detection HPRD
ATF3 CGA 15961508 27898060 stimulant N/A OmniPath
FOS CGA 15961508 27898060 stimulant N/A OmniPath
GSK3B CGA 2466636 27898060 N/A N/A OmniPath
JUN CGA 15961508 27898060 stimulant N/A OmniPath
CGA FSHR 2126341 27898060 stimulant N/A OmniPath
CGA TSHR 12045258 15571461 27898060 stimulant N/A OmniPath

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