Gene Information gene info

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GENE：CMA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CMA1
FullNmae chymase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2097
EnsembleID ENSG00000092009
Uniprot P23946

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CMA1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CMA1 GO:0002003,GO:0004175,GO:0004252,GO:0004252,GO:0005576,GO:0005576,GO:0005615,GO:0005737,GO:0005829,GO:0008236,GO:0022617,GO:0030141,GO:0030163,GO:0030901,GO:0034769,GO:0036464,GO:0042277,GO:0043231,GO:0045766,GO:0050727,GO:0062023,GO:0071333,GO:0140447

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CMA1 hsa:1215 path:hsa04614 Renin-angiotensin system - Homo sapiens (human)
CMA1 hsa:1215 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CMA1 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
CMA1 BGN 23180781 24257755 protein cleavage protease assay InnateDB
CMA1 HMGB1 23180781 24257755 protein cleavage protease assay InnateDB
CMA1 HSPA1A 23180781 24257755 protein cleavage protease assay InnateDB
CMA1 IL33 23180781 25313073 protein cleavage protease assay InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 CMA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CMA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CMA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CMA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CMA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CMA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CMA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
KITLG CMA1 25361965 interaction type N/A PTMCode2
CMA1 KITLG 25361965 interaction type N/A PTMCode2
CMA1 SERPINA3 25361965 interaction type N/A PTMCode2
SERPINA3 CMA1 25361965 interaction type N/A PTMCode2
CMA1 MMP1 25361965 interaction type N/A PTMCode2
MMP1 CMA1 25361965 interaction type N/A PTMCode2
CMA1 AGT 25361965 interaction type N/A PTMCode2
AGT CMA1 25361965 interaction type N/A PTMCode2
CMA1 EDN1 25361965 interaction type N/A PTMCode2
EDN1 CMA1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KITLG CMA1 10224464 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SERPINA3 CMA1 14525934 25348397 27898060 8226889 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CMA1 EDN3 14525934 25348397 9257865 N/A experimental interaction detection,in vitro ComPPI,HPRD
CMA1 PFN1 11751973 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CMA1 EDN1 14525934 25348397 9257865 N/A experimental interaction detection,in vitro ComPPI,HPRD
CMA1 AGT 10899625 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CMA1 IL1B 25348397 N/A physical interaction ComPPI
CMA1 FYN 25348397 N/A physical interaction ComPPI
CMA1 MMP1 14525934 8027075 N/A experimental interaction detection HPRD
CMA1 EDN2 14525934 9675146 N/A experimental interaction detection HPRD
CMA1 IL33 25313073 27898060 N/A N/A OmniPath
CMA1 MMP1 27898060 8027075 N/A N/A OmniPath

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