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GENE：COL4A5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COL4A5
FullNmae collagen type IV alpha 5 chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2207
EnsembleID ENSG00000188153
Uniprot P29400

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COL4A5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
COL4A5 GO:0005576,GO:0005587,GO:0005604,GO:0005615,GO:0005788,GO:0007528,GO:0030020,GO:0030020,GO:0030020,GO:0030198,GO:0031594,GO:0038063,GO:0062023

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COL4A5 hsa:1287 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa04510 Focal adhesion - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa05146 Amoebiasis - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa05200 Pathways in cancer - Homo sapiens (human)
COL4A5 hsa:1287 path:hsa05222 Small cell lung cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
COL4A5 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 COL4A5 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 COL4A5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 COL4A5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 COL4A5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 COL4A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA COL4A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COL4A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 COL4A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 COL4A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COL4A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COL4A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 COL4A5 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 COL4A5 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000153377 COL4A5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000031F6C2 COL4A5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000F7766 COL4A5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000029EBD COL4A5 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DCN COL4A5 25361965 interaction type N/A PTMCode2
COL4A5 DCN 25361965 interaction type N/A PTMCode2
COL4A5 COL4A6 25361965 interaction type N/A PTMCode2
COL4A6 COL4A5 25361965 interaction type N/A PTMCode2
COL4A5 MMP9 25361965 interaction type N/A PTMCode2
MMP9 COL4A5 25361965 interaction type N/A PTMCode2
COL4A5 COL4A3 25361965 interaction type N/A PTMCode2
COL4A3 COL4A5 25361965 interaction type N/A PTMCode2
COL4A5 SERPINE2 25361965 interaction type N/A PTMCode2
SERPINE2 COL4A5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDKN1A COL4A5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TK1 COL4A5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMN1 COL4A5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COL4A5 OSM 11711546 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL4A5 SERPINE2 14525934 25348397 8006028 N/A experimental interaction detection,in vivo ComPPI,HPRD
COL4A5 MATN2 12180907 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL4A5 HABP2 14525934 1724753 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
COL4A5 MMP9 14525934 25348397 9878537 N/A experimental interaction detection,in vivo ComPPI,HPRD
COL4A5 CD93 1377218 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
COL4A5 RNF10 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
COL4A5 DAZAP2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COL4A5 NR1H2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COL4A5 ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COL4A5 VHL 25348397 N/A physical interaction ComPPI
COL4A5 ELAVL1 25348397 N/A physical interaction ComPPI
COL4A5 ANTXR2 25348397 N/A physical interaction ComPPI
COL4A5 STRN3 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL4A5 PDK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL4A5 DAP3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL4A5 KIF21B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL4A5 KNL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL4A5 VPS26B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL4A5 PLOD1 25348397 N/A physical interaction ComPPI
COL4A5 HNRNPL 25348397 N/A physical interaction ComPPI
COL4A5 KLK6 12878203 24234451 25348397 protein cleavage protease assay ComPPI,IntAct
COL4A5 CEP170P1 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
COLGALT2 COL4A5 25348397 N/A physical interaction ComPPI
COL4A5 DCN 10382266 14525934 N/A experimental interaction detection HPRD
COL4A5 FN1 14525934 3997552 N/A experimental interaction detection HPRD
COL4A5 FBLN2 14525934 7500359 N/A experimental interaction detection HPRD
COL4A5 APP 14525934 9136074 N/A experimental interaction detection HPRD

Source Target Pmid Interactiontype Methods Database
URS00008B26D5 COL4A5 27087310 direct interaction,inhibition N/A NPInter

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