Gene Information gene info

  1. Home

GENE：CXCL10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CXCL10
FullNmae C-X-C motif chemokine ligand 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10637
EnsembleID ENSG00000169245
Uniprot P02778

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CXCL10 immunogenic 36579538 Through literature reviews, a total of 108 ICD-related genes were identified (Supplement Table S1). retulator signature

Go Annotation:

GeneSymbol Go id
CXCL10 GO:0005102,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0006935,GO:0006954,GO:0007165,GO:0007166,GO:0007186,GO:0007189,GO:0007267,GO:0007517,GO:0008009,GO:0008009,GO:0008015,GO:0008201,GO:0008284,GO:0008603,GO:0009897,GO:0010332,GO:0010818,GO:0010819,GO:0010996,GO:0016525,GO:0030593,GO:0033280,GO:0034605,GO:0042056,GO:0042118,GO:0042127,GO:0042981,GO:0045236,GO:0045662,GO:0045944,GO:0048248,GO:0050918,GO:0051281,GO:0061844,GO:0070098,GO:0070098,GO:0071222,GO:0071222,GO:0090026,GO:0097398,GO:0098586,GO:0140374,GO:1901509,GO:1901740,GO:2000406

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CXCL10 hsa:3627 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa05160 Hepatitis C - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa05164 Influenza A - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
CXCL10 hsa:3627 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HDAC3 CXCL10 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
NCOR1 CXCL10 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
PPARG CXCL10 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
TBL1X CXCL10 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
TBL1XR1 CXCL10 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 26192618 6357187 8871614 interaction type N/A ACSN
CD14 CXCL10 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
IRAK2 CXCL10 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
IRAK4 CXCL10 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
LY96 CXCL10 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
MYD88 CXCL10 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
TIRAP CXCL10 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 26192618 9743347 interaction type N/A ACSN
CXCL10 VCAN 11083865 23180781 physical association solid phase assay InnateDB
CXCL10 NFKB1 16253303 18986693 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
CXCL10 RELA 16253303 18986693 22030901 23180781 9794404 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
CXCL10 IRF1 16253303 17167270 18986693 23180781 9794404 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
CXCL10 IRF9 23180781 9794404 physical association electrophoretic mobility supershift assay InnateDB
CXCL10 IRF2 17167270 23180781 physical association electrophoretic mobility supershift assay InnateDB
CXCL10 IRF3 16253303 23180781 physical association affinity chromatography technology InnateDB
IRF7 CXCL10 16253303 20943654 23180781 physical association affinity chromatography technology,electrophoretic mobility supershift assay InnateDB
CXCL10 STAT1 19136629 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL10 PRMT1 19136629 23180781 physical association anti tag coimmunoprecipitation InnateDB
PIAS1 CXCL10 19136629 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL10 POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 CXCL10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IRF1 CXCL10 19342664 trascriptional regulation,stimulation inferred by curator TFlink
IRF3 CXCL10 18691624 24257594 trascriptional regulation,stimulation inferred by curator TFlink
IRF7 CXCL10 24701034 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 CXCL10 16818736 16982926 19479051 20164184 24257594 24701034 trascriptional regulation,stimulation inferred by curator TFlink
RELA CXCL10 16818736 16982926 19479051 20164184 24257594 24701034 trascriptional regulation,stimulation inferred by curator TFlink
STAT1 CXCL10 19479051 22022583 23153456 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D CXCL10 24889251 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS0000171525 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B CXCL10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B CXCL10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB CXCL10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 CXCL10 25416803 26845678 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CXCL10 DPP4 25361965 interaction type N/A PTMCode2
DPP4 CXCL10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CXCL9 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
PF4 CXCL10 24234451 25348397 28381538 N/A filter binding,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
CXCR3 CXCL10 25348397 N/A experimental interaction detection,physical interaction,physical interaction,biochemical,in vitro,in vivo ComPPI
CCL5 CXCL10 24234451 25348397 28381538 N/A filter binding,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
IGFBP7 CXCL10 12847218 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CCL13 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CCL8 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
DPP4 CXCL10 11390394 14525934 18275857 21314817 24234451 25348397 cleavage reaction experimental interaction detection,enzymatic study,protease assay,in vitro ComPPI,HPRD,IntAct
CXCL12 CXCL10 24234451 25348397 28381538 N/A filter binding,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
CCL11 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL11 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CCL28 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CCL21 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
XCL1 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CCL26 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
PPBP CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL10 CCR3 11110785 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CXCL10 DPP8 18275857 24234451 25348397 N/A enzymatic study ComPPI,IntAct
CXCL10 CXCL6 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL10 PF4V1 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL10 CXCL17 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL14 CXCL10 24234451 25348397 28381538 N/A filter binding ComPPI,IntAct
CXCL10 CXCL10 12737818 14525934 N/A experimental interaction detection HPRD
CXCL10 VCAN 11083865 14525934 N/A experimental interaction detection HPRD
IRF3 CXCL10 12354379 27898060 stimulant N/A OmniPath
CXCL10 CXCR3 10233762 12571234 15761110 24218476 27898060 9064356 9625760 9660793 stimulant N/A OmniPath
CXCL10 VCAN 11083865 27898060 N/A N/A OmniPath
CXCL10 DPP4 11390394 18275857 21314817 24218476 27898060 N/A N/A OmniPath
CXCL10 SDC4 20484822 27898060 N/A N/A OmniPath

Visualization










  Return