GENE:DDX19A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DDX19A |
| FullNmae | DEAD-box helicase 19A |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25628 |
| EnsembleID | ENSG00000168872 |
| Uniprot | Q9NUU7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DDX19A | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DDX19A | GO:0003674,GO:0003723,GO:0003724,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0008150,GO:0010043,GO:0010494,GO:0016020,GO:0016887,GO:0016973,GO:0043065 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| DDX19A | hsa:55308 | path:hsa03013 | Nucleocytoplasmic transport - Homo sapiens (human) |
| DDX19A | hsa:55308 | path:hsa03015 | mRNA surveillance pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | DDX19A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | DDX19A | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | DDX19A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DDX19A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | DDX19A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DDX19A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003D5391 | DDX19A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000001EB3 | DDX19A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000B59A2 | DDX19A | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CBE63 | DDX19A | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000081E1F | DDX19A | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | DDX19A | 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | DDX19A | 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | DDX19A | 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007340 | DDX19A | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | DDX19A | 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | DDX19A | 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | DDX19A | 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | DDX19A | 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000057FDB8 | DDX19A | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AB32B | DDX19A | 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | DDX19A | 21572407 23446348 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B6B84 | DDX19A | 21572407 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E0524 | DDX19A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023BE29 | DDX19A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | DDX19A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SNW1 | DDX19A | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CDC5L | DDX19A | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TOMM22 | DDX19A | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| NUP62 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| MDFI | DDX19A | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| AR | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| LIG4 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| SPTAN1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| PABPC1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| SPTBN1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| RAB11A | DDX19A | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| FUBP1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| HDAC6 | DDX19A | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| WDR12 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| RAB9A | DDX19A | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| NR3C1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| NUP88 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| EIF4E | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| BET1 | DDX19A | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| NUP214 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| DDX19B | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| NIF3L1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| MIF4GD | DDX19A | 14525934 16189514 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
| HSD17B10 | DDX19A | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| SEPHS1 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | SMARCAD1 | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | CCDC8 | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | DDX25 | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | IL4I1 | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | CTIF | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | G3BP1 | 25348397 | N/A | physical interaction | ComPPI |
| DDX19A | SFXN1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| HMGB3 | DDX19A | 25348397 | N/A | physical interaction | ComPPI |
| HSCB | DDX19A | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| SMARCB1 | DDX19A | 24234451 30108113 | association | proximity-dependent biotin identification | IntAct |
