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GENE：DMD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DMD
FullNmae dystrophin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2928
EnsembleID ENSG00000198947
Uniprot P11532

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DMD immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DMD GO:0002027,GO:0002162,GO:0003779,GO:0003779,GO:0005200,GO:0005515,GO:0005829,GO:0005856,GO:0007010,GO:0007517,GO:0007519,GO:0008104,GO:0008270,GO:0008307,GO:0008307,GO:0009986,GO:0010880,GO:0010881,GO:0014809,GO:0014819,GO:0016010,GO:0016010,GO:0016010,GO:0016013,GO:0016328,GO:0017022,GO:0017166,GO:0030018,GO:0030055,GO:0030175,GO:0031527,GO:0032991,GO:0033137,GO:0035633,GO:0035994,GO:0042383,GO:0042383,GO:0043034,GO:0043043,GO:0044306,GO:0045121,GO:0045202,GO:0045211,GO:0046716,GO:0048666,GO:0050998,GO:0055001,GO:0055001,GO:0060048,GO:0060314,GO:0065003,GO:0086001,GO:0090257,GO:0099536,GO:1901385,GO:1902083,GO:2000651

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DMD hsa:1756 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
DMD hsa:1756 path:hsa05412 Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)
DMD hsa:1756 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)
DMD hsa:1756 path:hsa05416 Viral myocarditis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DMD POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB
APP DMD 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR DMD 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 DMD 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 DMD 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 DMD 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SRF DMD 18971253 9032300 trascriptional regulation,stimulation inferred by curator TFlink
MYOD1 DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DMD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN DMD N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000001EB3 DMD 21212803 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000324096 DMD 17699775 25416803 mrna cleavage,inhibition array technology TarBase
URS0000001EB3 DMD 21212803 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 DMD 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000009262D DMD 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS000000EF0B DMD 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 DMD 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B DMD 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000013D17D DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F DMD 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DGKZ DMD 25361965 interaction type N/A PTMCode2
DMD DGKZ 25361965 interaction type N/A PTMCode2
ANK2 DMD 25361965 interaction type N/A PTMCode2
DMD ANK2 25361965 interaction type N/A PTMCode2
DAG1 DMD 25361965 interaction type N/A PTMCode2
DMD DAG1 25361965 interaction type N/A PTMCode2
USP16 DMD 25361965 interaction type N/A PTMCode2
DMD USP16 25361965 interaction type N/A PTMCode2
DMD PPP3CA 25361965 interaction type N/A PTMCode2
PPP3CA DMD 25361965 interaction type N/A PTMCode2
DMD SNTB1 25361965 interaction type N/A PTMCode2
SNTB1 DMD 25361965 interaction type N/A PTMCode2
DMD PGM5 25361965 interaction type N/A PTMCode2
PGM5 DMD 25361965 interaction type N/A PTMCode2
DMD DTNA 25361965 interaction type N/A PTMCode2
DTNA DMD 25361965 interaction type N/A PTMCode2
DMD MARK2 25361965 interaction type N/A PTMCode2
MARK2 DMD 25361965 interaction type N/A PTMCode2
SNTA1 DMD 25361965 interaction type N/A PTMCode2
DMD SNTA1 25361965 interaction type N/A PTMCode2
KCNJ12 DMD 25361965 interaction type N/A PTMCode2
DMD KCNJ12 25361965 interaction type N/A PTMCode2
SNTB2 DMD 25361965 interaction type N/A PTMCode2
DMD SNTB2 25361965 interaction type N/A PTMCode2
SGCA DMD 25361965 interaction type N/A PTMCode2
DMD SGCA 25361965 interaction type N/A PTMCode2
DMD SGCB 25361965 interaction type N/A PTMCode2
SGCB DMD 25361965 interaction type N/A PTMCode2
DMD SGCZ 25361965 interaction type N/A PTMCode2
SGCZ DMD 25361965 interaction type N/A PTMCode2
DMD DTNB 25361965 interaction type N/A PTMCode2
DTNB DMD 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT19 DMD 14525934 16000376 24234451 25348397 association,physical association experimental interaction detection,far western blotting,surface plasmon resonance,surface plasmon resonance array ComPPI,HPRD,IntAct
MCM2 DMD 25348397 N/A physical interaction ComPPI
TNS2 DMD 25348397 N/A physical interaction ComPPI
MAP3K5 DMD 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
KCNJ4 DMD 25348397 N/A physical interaction ComPPI
AHNAK DMD 25348397 N/A physical interaction ComPPI
UTRN DMD 10767429 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
XPO1 DMD 25348397 N/A physical interaction ComPPI
ARRB1 DMD 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DTNA DMD 10767429 14525934 24234451 25348397 9356463 9701558 physical association two hybrid,experimental interaction detection,filter binding,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
DAG1 DMD 10355629 10932245 22937058 24234451 25348397 27898060 7592992 N/A pull down,x-ray crystallography,physical interaction ComPPI,IntAct,OmniPath
MARK2 DMD 25348397 N/A physical interaction ComPPI
SNTA1 DMD 10545507 11571312 14525934 18468998 22937058 25348397 27898060 7890602 8576247 9412493 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
SIRT2 DMD 25348397 N/A physical interaction ComPPI
CTNNA1 DMD 25348397 N/A physical interaction ComPPI
KCNJ12 DMD 14525934 15024025 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NEDD4 DMD 25348397 N/A physical interaction ComPPI
SNTB1 DMD 14525934 24234451 25348397 7844150 8576247 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
SNTB2 DMD 14525934 24234451 25348397 8576247 physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
DTNB DMD 10545507 14525934 24234451 25348397 25416956 27898060 9395493 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct,OmniPath
SNTG2 DMD 10747910 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
ABCA1 DMD 24234451 25170080 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 DMD 25348397 N/A physical interaction ComPPI
CAVIN1 DMD 25348397 N/A physical interaction ComPPI
TERF1 DMD 25348397 N/A physical interaction ComPPI
NOS1 DMD 22937058 25348397 27898060 7545544 N/A physical interaction ComPPI,OmniPath
PALS2 DMD 25348397 N/A physical interaction ComPPI
TRAF3IP1 DMD 25348397 N/A physical interaction ComPPI
TERF2 DMD 25348397 N/A physical interaction ComPPI
KIF23 DMD 25348397 N/A physical interaction ComPPI
HAUS1 DMD 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CTNNAL1 DMD 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NUP58 DMD 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF15 DMD 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC25A DMD 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
KRT8 DMD 14525934 16000376 24234451 25348397 association experimental interaction detection,far western blotting ComPPI,HPRD,IntAct
LONRF3 DMD 25348397 N/A physical interaction ComPPI
ACTA1 DMD 11259305 14525934 1544421 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
ANK2 DMD 25348397 N/A pull down ComPPI
TRIM41 DMD 25348397 N/A physical interaction ComPPI
ALB DMD 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
IFIT5 DMD 25348397 N/A physical interaction ComPPI
APP DMD 25348397 N/A physical interaction ComPPI
DMD KCNJ18 25348397 N/A physical interaction ComPPI
DMD DISC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DMD NFX1 25348397 N/A physical interaction ComPPI
DMD LPAR6 25348397 N/A physical interaction ComPPI
DMD GAN 25348397 N/A physical interaction ComPPI
DMD TNS1 25348397 N/A physical interaction ComPPI
DMD TNS3 25348397 N/A physical interaction ComPPI
DMD HAUS4 25348397 N/A physical interaction ComPPI
DMD OSBPL1A 25348397 N/A physical interaction ComPPI
DMD LRRC8E 25348397 N/A physical interaction ComPPI
DMD WDR54 25348397 N/A physical interaction ComPPI
PGM5 DMD 10867799 14525934 7890770 N/A experimental interaction detection HPRD
DGKZ DMD 11352924 14525934 N/A experimental interaction detection HPRD
CADPS DMD 12659812 14525934 N/A two hybrid HPRD
SGCZ DMD 12189167 14525934 N/A experimental interaction detection HPRD
CADPS2 DMD 12659812 14525934 N/A two hybrid HPRD
SNTG1 DMD 10747910 11352924 14525934 N/A experimental interaction detection,two hybrid HPRD
DMD DMD 10801490 14525934 N/A experimental interaction detection HPRD
DMD ACTC1 11997265 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
DMD FASLG 11741599 14525934 N/A experimental interaction detection HPRD
PRKCSH DMD 24234451 30021884 physical association cross-linking study IntAct
SF3B2 DMD 24234451 30021884 physical association cross-linking study IntAct
H3-4 DMD 24234451 30021884 physical association cross-linking study IntAct

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