GENE:DMTN
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DMTN |
| FullNmae | dematin actin binding protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3382 |
| EnsembleID | ENSG00000158856 |
| Uniprot | Q08495 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DMTN | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DMTN | GO:0003779,GO:0005102,GO:0005515,GO:0005829,GO:0005829,GO:0005884,GO:0005886,GO:0005886,GO:0007010,GO:0008360,GO:0010591,GO:0010763,GO:0010801,GO:0010812,GO:0012505,GO:0014069,GO:0014731,GO:0015629,GO:0015629,GO:0030032,GO:0030036,GO:0030194,GO:0030507,GO:0030863,GO:0031095,GO:0031253,GO:0031410,GO:0032956,GO:0033137,GO:0035584,GO:0043621,GO:0048471,GO:0048821,GO:0050732,GO:0051015,GO:0051017,GO:0051017,GO:0051489,GO:0051693,GO:0051895,GO:0065003,GO:0065003,GO:0071277,GO:0071320,GO:0090303,GO:0090315,GO:1900025 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | DMTN | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | DMTN | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | DMTN | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | DMTN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DMTN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | DMTN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DMTN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | DMTN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | DMTN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000DDD35 | DMTN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005651EE | DMTN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001C770D | DMTN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000183BED | DMTN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000060AABB | DMTN | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170D8B | DMTN | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D1FC | DMTN | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AD450 | DMTN | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000585553 | DMTN | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000058BB84 | DMTN | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | DMTN | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PRKACA | DMTN | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GOLGA2 | DMTN | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| ACTB | DMTN | 14525934 25348397 8341682 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| YWHAG | DMTN | 25348397 | N/A | physical interaction | ComPPI |
| PRKACA | DMTN | 14525934 25348397 7615546 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| YWHAB | DMTN | 24234451 24255178 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| YWHAZ | DMTN | 25348397 | N/A | physical interaction | ComPPI |
| PROCR | DMTN | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| EPB42 | DMTN | 14525934 25348397 27898060 8608138 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| PKM | DMTN | 25348397 | N/A | protein kinase assay | ComPPI |
| TRAF2 | DMTN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| NEDD4L | DMTN | 25348397 | N/A | physical interaction | ComPPI |
| SPTB | DMTN | 14525934 25348397 8341682 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| YWHAE | DMTN | 25348397 | N/A | physical interaction | ComPPI |
| SNCA | DMTN | 25348397 | N/A | physical interaction | ComPPI |
| SNRPD2 | DMTN | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| SHMT2 | DMTN | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | PTOV1 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| DMTN | DYNC1LI2 | 14525934 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| DMTN | APP | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | TRAPPC10 | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | NUP188 | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | UBR1 | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | DPP9 | 25348397 | N/A | physical interaction | ComPPI |
| DMTN | CEP76 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| DMTN | ACTC1 | 12011427 14525934 27898060 | N/A | experimental interaction detection | HPRD,OmniPath |
| PRKACA | DMTN | 14660664 16472756 27898060 7615546 | N/A | N/A | OmniPath |
| CDK1 | DMTN | 27898060 7615546 | N/A | N/A | OmniPath |
