Gene Information gene info

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GENE：EAF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EAF2
FullNmae ELL associated factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23115
EnsembleID ENSG00000145088
Uniprot Q96CJ1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EAF2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EAF2 GO:0003711,GO:0003711,GO:0005515,GO:0005654,GO:0006368,GO:0006915,GO:0008023,GO:0008023,GO:0016607,GO:0030308,GO:0032783,GO:0034243,GO:0045944,GO:0060767,GO:0060770

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BIRC2 EAF2 23180781 25416956 physical association two hybrid InnateDB
TRIM23 EAF2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 EAF2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF EAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 EAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 EAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PML EAF2 18089734 trascriptional regulation,stimulation inferred by curator TFlink
TFPT EAF2 17395368 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 EAF2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 EAF2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 EAF2 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
EAF2 TFPT 25361965 interaction type N/A PTMCode2
TFPT EAF2 25361965 interaction type N/A PTMCode2
ELL EAF2 25361965 interaction type N/A PTMCode2
EAF2 ELL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RBPMS EAF2 25348397 N/A barcode fusion genetics two hybrid ComPPI
GOLGA2 EAF2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
TFPT EAF2 14525934 17395368 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
PNMA1 EAF2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
SIAH2 EAF2 25348397 N/A physical interaction ComPPI
HIF1A EAF2 24234451 24421387 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 EAF2 25348397 N/A physical interaction ComPPI
RBBP4 EAF2 25348397 N/A physical interaction ComPPI
TRIM23 EAF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TCEA1 EAF2 12761297 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
ELL EAF2 12446457 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MED26 EAF2 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TFIP11 EAF2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
EAF2 ELL2 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EAF2 AFF4 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EAF2 BIRC2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EAF2 BEND7 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EAF2 EAF1 25348397 N/A physical interaction ComPPI
EAF2 ELL3 25348397 N/A physical interaction ComPPI
EAF2 RBBP7 25348397 N/A physical interaction ComPPI
EAF2 PSME3 21516116 24234451 25348397 27107012 physical association two hybrid,physical interaction,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
EAF2 PIP4K2A 25348397 N/A physical interaction ComPPI
EAF2 IHO1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
EAF2 TP53 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
EAF2 STAC3 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
EAF2 TCEA2 12761297 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
LNX2 EAF2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
EAF2 EAF2 12446457 14525934 N/A experimental interaction detection HPRD
KIF4A EAF2 24234451 30021884 physical association cross-linking study IntAct
EAF2 ELL 12446457 16006523 27898060 stimulant N/A OmniPath

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