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GENE：ELK3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ELK3
FullNmae ETS transcription factor ELK3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3325
EnsembleID ENSG00000111145
Uniprot P41970

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ELK3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ELK3 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0001228,GO:0001525,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005739,GO:0006357,GO:0007165,GO:0030154,GO:0032422,GO:0042060,GO:0045892,GO:0045944,GO:1990837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP ELK3 21832049 23180781 physical association protein array InnateDB
MAPK8 ELK3 11042694 23331499 stimulation N/A SignaLink
MAPK3 ELK3 11042694 23331499 stimulation N/A SignaLink
MAPK14 ELK3 11042694 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR ELK3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ELK3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ELK3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ELK3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ELK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000055128B ELK3 19826008 25416803 mrna cleavage,inhibition array technology,rna immunoprecipitation,quantitative reverse transcription pcr TarBase
URS00000AA464 ELK3 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000600E6 ELK3 17242205 25416803 mrna cleavage,inhibition array technology TarBase
URS00003A5E54 ELK3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ELK3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 ELK3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 ELK3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 ELK3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A ELK3 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ELK3 NCK1 25361965 interaction type N/A PTMCode2
NCK1 ELK3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPK9 ELK3 11042694 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SP4 ELK3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRK ELK3 24234451 25348397 26871637 physical association two hybrid,two hybrid array,bimolecular fluorescence complementation,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DDIT4L ELK3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK8 ELK3 11042694 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PIK3R1 ELK3 17474147 24234451 25348397 25416956 physical association peptide array,mammalian protein protein interaction trap ComPPI,IntAct
NCK1 ELK3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 ELK3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PIAS1 ELK3 14525934 15580297 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
MAPK14 ELK3 11042694 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CTBP1 ELK3 10369679 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
HNRNPL ELK3 25348397 N/A physical interaction ComPPI
PFDN5 ELK3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDC37 ELK3 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ELK3 ID2 10022839 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ELK3 TCF3 14525934 25348397 27898060 8918463 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
ELK3 TOP1 25348397 N/A physical interaction ComPPI
ELK3 APP 25348397 N/A physical interaction ComPPI
ELK3 BPIFA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRC ELK3 11042694 27898060 N/A N/A OmniPath
MAPK14 ELK3 11042694 27898060 9130707 stimulant N/A OmniPath
CTBP1 ELK3 10369679 14693367 27898060 inhibition N/A OmniPath

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