GENE：FABP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FABP1 |
| FullNmae | fatty acid binding protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3555 |
| EnsembleID | ENSG00000163586 |
| Uniprot | P07148 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FABP1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| FABP1 | GO:0003682,GO:0005324,GO:0005504,GO:0005515,GO:0005543,GO:0005634,GO:0005654,GO:0005654,GO:0005782,GO:0005829,GO:0005829,GO:0005829,GO:0015908,GO:0015909,GO:0016209,GO:0032000,GO:0032052,GO:0032991,GO:0043066,GO:0043154,GO:0045179,GO:0050892,GO:0070062,GO:0070301,GO:0070538,GO:0071456,GO:0098869,GO:1901363 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| FABP1 | hsa:2168 | path:hsa03320 | PPAR signaling pathway - Homo sapiens (human) |
| FABP1 | hsa:2168 | path:hsa04936 | Alcoholic liver disease - Homo sapiens (human) |
| FABP1 | hsa:2168 | path:hsa04975 | Fat digestion and absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | FABP1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | FABP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | FABP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | FABP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | FABP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | FABP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | FABP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF1A | FABP1 | 20357450 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| AR | FABP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARA | FABP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FABP1 | PPARA | 25348397 | N/A | two hybrid,physical interaction,in vitro,in vivo | ComPPI |
| FABP1 | PPARG | 11226238 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| FABP1 | GRB2 | 18624398 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| FABP1 | SNTA1 | 25348397 | N/A | physical interaction | ComPPI |
| FABP1 | FLNA | 24234451 25348397 25910212 | physical association | physical interaction,two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| FABP1 | EPHA4 | 25348397 | N/A | physical interaction | ComPPI |
| FABP1 | GNPNAT1 | 25348397 | N/A | physical interaction | ComPPI |