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GENE：FCER2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FCER2
FullNmae Fc epsilon receptor II
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3612
EnsembleID ENSG00000104921
Uniprot P06734

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FCER2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FCER2 GO:0002450,GO:0002925,GO:0005178,GO:0005515,GO:0005886,GO:0005886,GO:0006955,GO:0009897,GO:0019769,GO:0019863,GO:0030246,GO:0038095,GO:0042116,GO:0044419,GO:0046872,GO:0051000,GO:0051712,GO:0051770,GO:0070062,GO:0160006

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FCER2 hsa:2208 path:hsa04640 Hematopoietic cell lineage - Homo sapiens (human)
FCER2 hsa:2208 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FCER2 REL 16896156 23180781 physical association electrophoretic mobility supershift assay InnateDB
FCER2 IRF4 10601358 11342629 23180781 physical association electrophoretic mobility supershift assay InnateDB
FCER2 BCL6 10601358 23180781 physical association electrophoretic mobility supershift assay InnateDB
FCER2 STAT6 10601358 21268015 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
FCER2 CEBPB 19487031 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBPJ FCER2 19487031 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 FCER2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FCER2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 FCER2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 FCER2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FCER2 18971253 9300687 trascriptional regulation,stimulation inferred by curator TFlink
BCL6 FCER2 11342629 trascriptional regulation,stimulation inferred by curator TFlink
IRF4 FCER2 11342629 trascriptional regulation,stimulation inferred by curator TFlink
PAX5 FCER2 12731041 trascriptional regulation,stimulation inferred by curator TFlink
STAT6 FCER2 9686563 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
FCER2 FYN 1387715 1446976 14525934 1717997 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FCER2 CR2 14525934 25348397 27898060 7515913 8766552 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
FCER2 ITGAX 14525934 25348397 7621072 N/A experimental interaction detection,in vivo ComPPI,HPRD
FCER2 ITGB2 25348397 N/A in vivo ComPPI
FCER2 STAT6 25348397 N/A physical interaction ComPPI
FCER2 PARP14 25348397 N/A physical interaction ComPPI
FCER2 ATF7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

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