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GENE：FKBP1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FKBP1A
FullNmae FKBP prolyl isomerase 1A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3711
EnsembleID ENSG00000088832
Uniprot P62942

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FKBP1A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FKBP1A GO:0000413,GO:0000413,GO:0003007,GO:0003755,GO:0003755,GO:0003755,GO:0005160,GO:0005160,GO:0005515,GO:0005527,GO:0005528,GO:0005528,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006457,GO:0006458,GO:0014802,GO:0016020,GO:0016529,GO:0022417,GO:0030018,GO:0030512,GO:0030547,GO:0032092,GO:0032515,GO:0032880,GO:0032926,GO:0033017,GO:0034713,GO:0034713,GO:0042026,GO:0042110,GO:0043123,GO:0044325,GO:0044325,GO:0050776,GO:0055010,GO:0060314,GO:0060314,GO:0060314,GO:0060347,GO:0070411,GO:0070588,GO:0070697,GO:0097435,GO:0098562,GO:1902991,GO:1990000,GO:1990425

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FKBP1A TGFBR1 11226255 14766396 16720724 23331499 26192618 interaction type,stimulation N/A ACSN,SignaLink
FKBP1A TGFBR2 11226255 14766396 26192618 interaction type N/A ACSN
FKBP1A MTOR 23180781 9334222 physical association pull down InnateDB
ACVR1B FKBP1A 16720724 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 FKBP1A 16720724 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
SMURF1 FKBP1A 16720724 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP FKBP1A 21832049 23180781 physical association protein array InnateDB
FKBP1A ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB
FKBP1A FKBP1A 10789724 10877843 11447115 12953056 1333888 15761148 20207738 20625381 21258369 21358634 23525077 26467481 29145629 7693660 7823948 8242743 8756725 9233797 9927040 bind,physical association,down-regulates activity inferred by curator Reactome,Signor

Source Target Pmid Interactiontype Methods Database
RPTOR FKBP1A 20005715 interaction type N/A PSP
RPTOR FKBP1A 15268862 15467718 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR FKBP1A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FKBP1A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FKBP1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 FKBP1A 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000017EA6A FKBP1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD FKBP1A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000018C928 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000019F055 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 FKBP1A 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 FKBP1A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 FKBP1A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6479 FKBP1A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016C318 FKBP1A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE FKBP1A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E FKBP1A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000024DFCE FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 FKBP1A 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FKBP1A ACVR1 25361965 interaction type N/A PTMCode2
ACVR1 FKBP1A 25361965 interaction type N/A PTMCode2
FKBP1A FKBP1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 FKBP1A 25348397 N/A physical interaction ComPPI
FABP3 FKBP1A 25348397 N/A physical interaction ComPPI
FKBP1A AHSP 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FKBP1A SF3B4 25348397 N/A two hybrid,physical interaction ComPPI
FKBP1A RYR1 11171121 11237759 11279144 12704193 14525934 18268335 24234451 25348397 27898060 8521476 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
FKBP1A RYR3 11171121 11598113 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
FKBP1A YY1 14525934 25348397 27898060 7541038 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
FKBP1A GLMN 14525934 25348397 8955134 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FKBP1A TGFB1I1 12417722 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FKBP1A FKBP4 11164950 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
FKBP1A TRPC3 14525934 15199065 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FKBP1A PPP3CA 14525934 25348397 7543369 8524402 N/A experimental interaction detection,in vitro ComPPI,HPRD
FKBP1A MTOR 10089303 14525934 17148612 22664266 24234451 25348397 29997244 8662507 physical association beta galactosidase complementation,bioluminescence resonance energy transfer,biophysical,experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,biochemical,in vitro,luminescence based mammalian interactome mapping,proximity ligation assay ComPPI,HPRD,IntAct
FKBP1A DHFR 12812497 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
FKBP1A ITPR1 14525934 16278292 25348397 27898060 8521476 9346894 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
FKBP1A TGFBR1 10025408 14525934 24234451 24658140 25348397 7518616 9346894 physical association experimental interaction detection,ubiquitin reconstruction,x-ray crystallography,physical interaction,two hybrid ComPPI,HPRD,IntAct
FKBP1A RPTOR 25348397 N/A physical interaction ComPPI
FKBP1A BMPR1A 25348397 N/A physical interaction ComPPI
FKBP1A TGFB1 25348397 N/A physical interaction ComPPI
FKBP1A ACVR1B 16720724 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
FKBP1A SMAD7 16720724 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
FKBP1A ELAVL1 25348397 N/A physical interaction ComPPI
FKBP1A APP 25348397 N/A physical interaction ComPPI
FKBP1A ZPR1 25348397 N/A physical interaction ComPPI
FKBP1A BARD1 25348397 N/A physical interaction ComPPI
FKBP1A ACVRL1 25348397 N/A physical interaction ComPPI
FKBP1A BAG3 25348397 N/A physical interaction ComPPI
FKBP1A MID1 25348397 N/A physical interaction ComPPI
FKBP1A CTBP1 25348397 N/A physical interaction ComPPI
FKBP1A AGL 25348397 N/A physical interaction ComPPI
FKBP1A ENO1 25348397 N/A physical interaction ComPPI
FKBP1A ENO2 25348397 N/A physical interaction ComPPI
FKBP1A ENO3 25348397 N/A physical interaction ComPPI
FKBP1A FABP5P3 25348397 N/A physical interaction ComPPI
FKBP1A FABP5 25348397 N/A physical interaction ComPPI
FKBP1A FKBP2 25348397 N/A physical interaction ComPPI
FKBP1A GPX4 25348397 N/A physical interaction ComPPI
FKBP1A GSTO2 25348397 N/A physical interaction ComPPI
FKBP1A HINT1 25348397 N/A physical interaction ComPPI
FKBP1A MSI2 25348397 N/A physical interaction ComPPI
FKBP1A NME2 25348397 N/A physical interaction ComPPI
FKBP1A PPIB 25348397 N/A physical interaction ComPPI
FKBP1A RAE1 25348397 N/A physical interaction ComPPI
FKBP1A SOD1 25348397 N/A physical interaction ComPPI
FKBP1A TAGLN 25348397 N/A physical interaction ComPPI
FKBP1A TAGLN2 25348397 N/A physical interaction ComPPI
FKBP1A TAGLN3 25348397 N/A physical interaction ComPPI
FKBP1A UFC1 25348397 N/A physical interaction ComPPI
FKBP1A YKT6 25348397 N/A physical interaction ComPPI
FKBP1A GSTT1 25348397 N/A physical interaction ComPPI
FKBP1A HSD17B10 25348397 N/A physical interaction ComPPI
FKBP1A HSPE1 25348397 N/A physical interaction ComPPI
FKBP1A NMRAL1 25348397 N/A physical interaction ComPPI
FKBP1A PPIF 25348397 N/A physical interaction ComPPI
FKBP1A PPP4R3A 25348397 N/A physical interaction ComPPI
FKBP1A TXN 25348397 N/A physical interaction ComPPI
FKBP1A MED20 25348397 N/A physical interaction ComPPI
FKBP1A TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP1A NAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP1A MCM2 25348397 N/A physical interaction ComPPI
FKBP1A NLGN3 25348397 N/A physical interaction ComPPI
FKBP1A MDM2 25348397 N/A physical interaction ComPPI
FKBP1A VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FKBP1A EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FKBP1A RYR2 11237759 24234451 25348397 physical association competition binding ComPPI,IntAct
FKBP1A FKBP1B 11237759 24234451 25348397 physical association competition binding ComPPI,IntAct
FKBP1A SMAD6 16720724 24234451 25348397 physical association two hybrid ComPPI,IntAct
FKBP1A SHLD3 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
FKBP1A FKBP1A 10852943 11438723 14525934 8521476 8662507 9346894 9871618 N/A experimental interaction detection HPRD
RPS9 FKBP1A 24234451 30021884 physical association cross-linking study IntAct
MTOR FKBP1A 10089303 15268862 15284440 15467718 15796538 17145710 17991864 26344197 27898060 7822316 8662507 9334222 N/A N/A OmniPath
FKBP1A MTOR 10089303 15268862 15284440 15467718 15796538 17145710 17991864 26344197 27898060 7822316 8662507 9334222 inhibition N/A OmniPath
FKBP1A TGFBR1 10025408 16720724 24658140 27898060 7518616 7791754 8756725 9346894 inhibition,stimulant N/A OmniPath

Visualization










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