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GENE：FOSB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FOSB
FullNmae FosB proto-oncogene, AP-1 transcription factor subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3797
EnsembleID ENSG00000125740
Uniprot P53539

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FOSB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FOSB GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006357,GO:0006366,GO:0007565,GO:0009410,GO:0009612,GO:0032570,GO:0032870,GO:0043231,GO:0045944,GO:0051412,GO:0051591,GO:0071277,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FOSB hsa:2354 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
FOSB hsa:2354 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
FOSB hsa:2354 path:hsa05030 Cocaine addiction - Homo sapiens (human)
FOSB hsa:2354 path:hsa05031 Amphetamine addiction - Homo sapiens (human)
FOSB hsa:2354 path:hsa05034 Alcoholism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELF1 FOSB 23180781 7648395 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FOSB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FOSB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FOSB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA FOSB 20018891 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 FOSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FOSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FOSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FOSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FOSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FOSB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
STAT6 FOSB 18342537 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000184017 FOSB 20065103 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000184017 FOSB 20065103 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00004929F1 FOSB 21378144 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 FOSB 22135298 phosphorylation N/A PhosphoSite
FOSB JUND 25361965 interaction type N/A PTMCode2
JUND FOSB 25361965 interaction type N/A PTMCode2
FOSB JUNB 25361965 interaction type N/A PTMCode2
JUNB FOSB 25361965 interaction type N/A PTMCode2
FOSB JUN 25361965 interaction type N/A PTMCode2
JUN FOSB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ROR2 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG3 FOSB 25348397 N/A physical interaction ComPPI
ZC3H10 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUNB FOSB 12371906 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct
JUN FOSB 24234451 25348397 25609649 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CREBBP FOSB 25348397 N/A physical interaction ComPPI
EP300 FOSB 25348397 N/A physical interaction ComPPI
JUND FOSB 10942775 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MECOM FOSB 22308434 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
POGZ FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DNMT3L FOSB 25348397 N/A physical interaction ComPPI
TLX3 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TENT5B FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATF2 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOXP3 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AGXT FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ENKD1 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PHF1 FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CENPO FOSB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOSB SRA1 25348397 N/A physical interaction ComPPI
FOSB FOS 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOSB CYTH4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOSB FAM222B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOSB GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOSB VEZF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOSB POU6F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FOSB MTA1 21258411 27898060 N/A N/A OmniPath
CSNK2A1 FOSB 16687504 17241283 27898060 stimulant N/A OmniPath

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