Gene Information gene info

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GENE：GDF15

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GDF15
FullNmae growth differentiation factor 15
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30142
EnsembleID ENSG00000130513
Uniprot Q99988

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GDF15 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GDF15 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GDF15 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GDF15 GO:0002023,GO:0005125,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005634,GO:0005737,GO:0005794,GO:0007165,GO:0007179,GO:0007267,GO:0008083,GO:0035860,GO:0040015,GO:0042803,GO:0043410,GO:0043410,GO:0051897,GO:0051897,GO:0060395,GO:0060400,GO:0062023,GO:0070062,GO:1901741

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GDF15 hsa:9518 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 GDF15 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 GDF15 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GDF15 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A GDF15 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 GDF15 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA GDF15 15757899 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 GDF15 10618379 10777512 18971253 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 GDF15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GDF15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GDF15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GDF15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GDF15 14662774 17715378 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GDF15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GDF15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GDF15 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF3 GDF15 15670751 trascriptional regulation,stimulation inferred by curator TFlink
CEBPB GDF15 24086573 trascriptional regulation,stimulation inferred by curator TFlink
KLF4 GDF15 20385121 22750490 trascriptional regulation,stimulation inferred by curator TFlink
PPARG GDF15 14662774 trascriptional regulation,stimulation inferred by curator TFlink
TWIST1 GDF15 19051271 trascriptional regulation,stimulation inferred by curator TFlink
TWIST2 GDF15 19051271 trascriptional regulation,stimulation inferred by curator TFlink
SMAD1 GDF15 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 GDF15 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00002EF20A GDF15 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000821E0 GDF15 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000013ABA3 GDF15 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004C6C6F GDF15 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004C689A GDF15 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B GDF15 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000553F51 GDF15 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HOXA1 GDF15 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MDFI GDF15 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach ComPPI,IntAct
TACC3 GDF15 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK14 GDF15 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
STAT5A GDF15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAE1 GDF15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GDF15 CBX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TP53 GDF15 17276395 27898060 stimulant N/A OmniPath
GDF15 ERBB2 27898060 6328316 stimulant N/A OmniPath
SP1 GDF15 11895857 27898060 stimulant N/A OmniPath

Visualization










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