GENE：GJB6
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GJB6 |
| FullNmae | gap junction protein beta 6 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4288 |
| EnsembleID | ENSG00000121742 |
| Uniprot | O95452 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GJB6 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GJB6 | GO:0003163,GO:0005243,GO:0005243,GO:0005515,GO:0005884,GO:0005921,GO:0005921,GO:0005922,GO:0007267,GO:0007605,GO:0008017,GO:0008285,GO:0010644,GO:0016264,GO:0016264,GO:0016324,GO:0030054,GO:0032496,GO:0035633,GO:0042471,GO:0048487,GO:0048839,GO:0051015,GO:0051602,GO:0055085,GO:0071333,GO:1903763,GO:1990349,GO:1990349 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | GJB6 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | GJB6 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CTCF | GJB6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | GJB6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | GJB6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EBP | GJB6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SEC22B | GJB6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| GJB2 | GJB6 | 14525934 14595769 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| GJB6 | KLRC1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| F2RL1 | GJB6 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
| CHRM5 | GJB6 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
| GJB6 | GJB2 | 14595769 19047647 27898060 | stimulant | N/A | OmniPath |
| GJB2 | GJB6 | 14595769 19047647 27898060 | stimulant | N/A | OmniPath |