Gene Information gene info

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GENE：HAT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HAT1
FullNmae histone acetyltransferase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4821
EnsembleID ENSG00000128708
Uniprot O14929

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HAT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HAT1 GO:0000781,GO:0000785,GO:0004402,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005739,GO:0006334,GO:0006475,GO:0010485,GO:0016363,GO:0031509,GO:0032991,GO:0042393,GO:0043997,GO:0051276

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HAT1 hsa:8520 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
HAT1 hsa:8520 path:hsa05034 Alcoholism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 HAT1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 HAT1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HAT1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 HAT1 19559773 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 HAT1 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF HAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A HAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB HAT1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002FC5B0 HAT1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00004AC389 HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 HAT1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F HAT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 HAT1 20371350 21572407 22012620 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 HAT1 20371350 21572407 22012620 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B HAT1 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 HAT1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 HAT1 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HAT1 RBBP4 25361965 interaction type N/A PTMCode2
RBBP4 HAT1 25361965 interaction type N/A PTMCode2
HAT1 RBBP7 25361965 interaction type N/A PTMCode2
RBBP7 HAT1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PRKAA2 HAT1 25348397 N/A physical interaction ComPPI
HAT1 MEOX2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HAT1 SMAD7 12408818 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HAT1 BAP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAT1 G3BP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAT1 ATG10 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAT1 H4C1 19862764 22615379 24234451 25348397 27898060 acetylation reaction,association,physical association x-ray crystallography,acetylation reaction,physical interaction,tandem affinity purification,acetylase assay ComPPI,IntAct,OmniPath
HAT1 H3-4 25348397 N/A physical interaction ComPPI
HAT1 RBBP7 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
HAT1 ASF1B 25348397 N/A physical interaction ComPPI
HAT1 IPO4 25348397 N/A physical interaction ComPPI
HAT1 H3C1 19410544 19498464 20080577 24234451 25348397 29568061 association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
HAT1 H3-3A 25348397 N/A physical interaction ComPPI
HAT1 H2AX 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAT1 BCL2A1 25348397 N/A physical interaction ComPPI
HAT1 CUL3 25348397 N/A physical interaction ComPPI
HAT1 COPS5 25348397 N/A physical interaction ComPPI
HAT1 ACAA1 25348397 N/A physical interaction ComPPI
HAT1 H2AC20 25348397 N/A physical interaction ComPPI
HAT1 TP53BP1 25348397 N/A physical interaction ComPPI
HAT1 YWHAQ 25348397 N/A physical interaction ComPPI
HAT1 ZGPAT 25348397 N/A physical interaction ComPPI
HAT1 HSPA1A 25348397 N/A physical interaction ComPPI
HAT1 HSPA1B 25348397 N/A physical interaction ComPPI
HAT1 RBBP4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HAT1 REL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HAT1 TCF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HAT1 TNFAIP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HAT1 RPS6KB2 25348397 N/A physical interaction ComPPI
HAT1 UNK 25348397 N/A physical interaction ComPPI
HAT1 C5ORF51 25348397 N/A physical interaction ComPPI
HAT1 AP2M1 25348397 N/A physical interaction ComPPI
HAT1 DDI2 25348397 N/A physical interaction ComPPI
HAT1 TTC4 25348397 N/A physical interaction ComPPI
HAT1 VPS29 25348397 N/A physical interaction ComPPI
HAT1 SNF8 25348397 N/A physical interaction ComPPI
HAT1 TLN2 25348397 N/A physical interaction ComPPI
HAT1 NTRK1 25348397 N/A physical interaction ComPPI
HAT1 NASP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAT1 ASF1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAT1 CRY2 25348397 N/A physical interaction ComPPI
HAT1 FAM204A 25348397 N/A physical interaction ComPPI
HAT1 VTN 25348397 N/A physical interaction ComPPI
HAT1 YWHAZ 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
HAT1 UBE2A 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
HAT1 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HAT1 EPOP 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
HAT1 AIM2 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
HAT1 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
HAT1 TRIB3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HAT1 KANK4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HAT1 STEEP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HAT1 MORN5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HAT1 ZSCAN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HAT1 LACC1 24234451 25348397 27478939 association affinity chromatography technology ComPPI,IntAct
HAT1 HSCB 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
HAT1 CDK8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HAT1 XPO7 24234451 25348397 29748336 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HTR2B HAT1 24234451 28298427 physical association ubiquitin reconstruction IntAct
HAT1 SETD2 14761951 17880717 20953179 27898060 N/A N/A OmniPath
HAT1 BIN2 24164091 27898060 N/A N/A OmniPath
HAT1 H3-4 10911985 20953179 23281010 27898060 stimulant N/A OmniPath
HAT1 SMAD7 12408818 27898060 N/A N/A OmniPath

Visualization










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