Gene Information gene info

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GENE：HLA-DPA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HLA-DPA1
FullNmae major histocompatibility complex, class II, DP alpha 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4938
EnsembleID ENSG00000231389
Uniprot P20036

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HLA-DPA1 immunogenic 36579538 Through literature reviews, a total of 108 ICD-related genes were identified (Supplement Table S1). retulator signature
HLA-DPA1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HLA-DPA1 GO:0000139,GO:0002250,GO:0002503,GO:0005765,GO:0005765,GO:0005886,GO:0005886,GO:0006955,GO:0009986,GO:0012507,GO:0019886,GO:0019886,GO:0023026,GO:0030658,GO:0030666,GO:0030669,GO:0031902,GO:0032395,GO:0032588,GO:0032729,GO:0042102,GO:0042605,GO:0042605,GO:0042613,GO:0042613,GO:0043231,GO:0050778,GO:0050870,GO:0050870,GO:0071346,GO:0098553

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HLA-DPA1 hsa:3113 path:hsa04145 Phagosome - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa04612 Antigen processing and presentation - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa04640 Hematopoietic cell lineage - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa04672 Intestinal immune network for IgA production - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa04940 Type I diabetes mellitus - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05140 Leishmaniasis - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05150 Staphylococcus aureus infection - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05152 Tuberculosis - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05164 Influenza A - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05310 Asthma - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05320 Autoimmune thyroid disease - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05321 Inflammatory bowel disease - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05330 Allograft rejection - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05332 Graft-versus-host disease - Homo sapiens (human)
HLA-DPA1 hsa:3113 path:hsa05416 Viral myocarditis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HLA-DPA1 HLA-DPA1 10480952 10540230 11529500 11684289 11790530 12078484 12748383 14731593 16618111 16824007 18292509 1956401 24243840 29145629 7650016 8134367 8397411 8520027 8687433 9312039 9850860 enzymatic reaction,physical association inferred by curator Reactome
HLA-DQA1 HLA-DPA1 10480952 10540230 11529500 11684289 11790530 12078484 12748383 14731593 16618111 16824007 18292509 1956401 24243840 29145629 7650016 8134367 8397411 8520027 8687433 9312039 9850860 enzymatic reaction,physical association inferred by curator Reactome
HLA-DRA HLA-DPA1 10480952 10540230 11529500 11684289 11790530 12078484 12748383 14731593 16618111 16824007 18292509 1956401 24243840 29145629 7650016 8134367 8397411 8520027 8687433 9312039 9850860 enzymatic reaction,physical association inferred by curator Reactome
HLA-DQA2 HLA-DPA1 10480952 10540230 11529500 11684289 11790530 12078484 12748383 14731593 16618111 16824007 18292509 1956401 24243840 29145629 7650016 8134367 8397411 8520027 8687433 9312039 9850860 enzymatic reaction,physical association inferred by curator Reactome
HLA-DPA1 PTPN6 12947224 15358536 18173375 18759926 29145629 dephosphorylation reaction inferred by curator Reactome
PLCG1 HLA-DPA1 11048639 29145629 enzymatic reaction inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
YBX1 HLA-DPA1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HLA-DPA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HLA-DPA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HLA-DPA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HLA-DPA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 HLA-DPA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RFX5 HLA-DPA1 11258423 trascriptional regulation,stimulation inferred by curator TFlink
RFXANK HLA-DPA1 11258423 trascriptional regulation,stimulation inferred by curator TFlink
RFXAP HLA-DPA1 11258423 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 HLA-DPA1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GAL HLA-DPA1 25348397 N/A physical interaction ComPPI
HBD HLA-DPA1 25348397 N/A physical interaction ComPPI
HLA-DPB1 HLA-DPA1 14525934 25348397 27898060 8649448 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
NMU HLA-DPA1 25348397 N/A physical interaction ComPPI
HBA1 HLA-DPA1 25348397 N/A physical interaction ComPPI
TAF6L HLA-DPA1 25348397 N/A physical interaction ComPPI
CD4 HLA-DPA1 12899833 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CLU HLA-DPA1 25348397 N/A physical interaction ComPPI
APOE HLA-DPA1 25348397 N/A physical interaction ComPPI
SCARB1 HLA-DPA1 25348397 N/A physical interaction ComPPI
PTPRS HLA-DPA1 25348397 N/A physical interaction ComPPI
SREBF2 HLA-DPA1 25348397 N/A physical interaction ComPPI
LNPEP HLA-DPA1 25348397 N/A physical interaction ComPPI
DAG1 HLA-DPA1 25348397 N/A physical interaction ComPPI
EFNB1 HLA-DPA1 25348397 N/A physical interaction ComPPI
EPHA4 HLA-DPA1 25348397 N/A physical interaction ComPPI
KIDINS220 HLA-DPA1 25348397 N/A physical interaction ComPPI
PDK1 HLA-DPA1 25348397 N/A physical interaction ComPPI
NUCB1 HLA-DPA1 25348397 N/A physical interaction ComPPI
HLA-A HLA-DPA1 25348397 N/A physical interaction ComPPI
HLA-F HLA-DPA1 25348397 N/A physical interaction ComPPI
KIRREL1 HLA-DPA1 25348397 N/A physical interaction ComPPI
EPHA7 HLA-DPA1 25348397 N/A physical interaction ComPPI
TNFSF9 HLA-DPA1 25348397 N/A physical interaction ComPPI
EFNB3 HLA-DPA1 25348397 N/A physical interaction ComPPI
SORL1 HLA-DPA1 25348397 N/A physical interaction ComPPI
RPL23 HLA-DPA1 25348397 N/A physical interaction ComPPI
ASPM HLA-DPA1 25348397 N/A physical interaction ComPPI
QSOX1 HLA-DPA1 25348397 N/A physical interaction ComPPI
RMDN3 HLA-DPA1 25348397 N/A physical interaction ComPPI
TOR1B HLA-DPA1 25348397 N/A physical interaction ComPPI
MTX1 HLA-DPA1 25348397 N/A physical interaction ComPPI
NOB1 HLA-DPA1 25348397 N/A physical interaction ComPPI
GALNT11 HLA-DPA1 25348397 N/A physical interaction ComPPI
DIMT1 HLA-DPA1 25348397 N/A physical interaction ComPPI
SERPINB4 HLA-DPA1 25348397 N/A physical interaction ComPPI
CD74 HLA-DPA1 14525934 16242130 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
ULBP3 HLA-DPA1 25348397 N/A physical interaction ComPPI
NF1 HLA-DPA1 25348397 N/A physical interaction ComPPI
HOXA5 HLA-DPA1 25348397 N/A physical interaction ComPPI
LTBP1 HLA-DPA1 25348397 N/A physical interaction ComPPI
POM121 HLA-DPA1 25348397 N/A physical interaction ComPPI
HOXD13 HLA-DPA1 25348397 N/A physical interaction ComPPI
B4GALT3 HLA-DPA1 25348397 N/A physical interaction ComPPI
RER1 HLA-DPA1 25348397 N/A physical interaction ComPPI
LRFN1 HLA-DPA1 25348397 N/A physical interaction ComPPI
HLA-DPA1 MYO9B 25348397 N/A physical interaction ComPPI
HLA-DPA1 GOLIM4 25348397 N/A physical interaction ComPPI
HLA-DPA1 SLC22A18 25348397 N/A physical interaction ComPPI
HLA-DPA1 ATP13A2 25348397 N/A physical interaction ComPPI
HLA-DPA1 C17ORF80 25348397 N/A physical interaction ComPPI
HLA-DPA1 ABCB6 25348397 N/A physical interaction ComPPI
HLA-DPA1 SLC38A10 25348397 N/A physical interaction ComPPI
HLA-DPA1 DSE 25348397 N/A physical interaction ComPPI
HLA-DPA1 NDUFA3 25348397 N/A physical interaction ComPPI
HLA-DPA1 PNPLA6 25348397 N/A physical interaction ComPPI
HLA-DPA1 DCBLD1 25348397 N/A physical interaction ComPPI
HLA-DPA1 PGAP4 25348397 N/A physical interaction ComPPI
HLA-DPA1 FKTN 25348397 N/A physical interaction ComPPI
HLA-DPA1 QSOX2 25348397 N/A physical interaction ComPPI
HLA-DPA1 SLC25A16 25348397 N/A physical interaction ComPPI
HLA-DPA1 LPCAT2 25348397 N/A physical interaction ComPPI
HLA-DPA1 FUT4 25348397 N/A physical interaction ComPPI
HLA-DPA1 NUS1 25348397 N/A physical interaction ComPPI
HLA-DPA1 NCR3LG1 25348397 N/A physical interaction ComPPI
HLA-DPA1 TYW5 25348397 N/A physical interaction ComPPI
HLA-DPA1 ATP2C1 25348397 N/A physical interaction ComPPI
HLA-DPA1 FAM210A 25348397 N/A physical interaction ComPPI
HLA-DPA1 HS3ST3B1 25348397 N/A physical interaction ComPPI
HLA-DPA1 SFXN1 25348397 N/A physical interaction ComPPI
HLA-DPA1 CHSY1 25348397 N/A physical interaction ComPPI
HLA-DPA1 INTS7 25348397 N/A physical interaction ComPPI
HLA-DPA1 B4GALT4 25348397 N/A physical interaction ComPPI
HLA-DPA1 ITFG1 25348397 N/A physical interaction ComPPI
HLA-DPA1 TMEM201 25348397 N/A physical interaction ComPPI
HLA-DPA1 ABCB10 25348397 N/A physical interaction ComPPI
HLA-DPA1 EGFL7 25348397 N/A physical interaction ComPPI
HLA-DPA1 SLC25A15 25348397 N/A physical interaction ComPPI
HLA-DPA1 GPAT3 25348397 N/A physical interaction ComPPI
HLA-DPA1 PCDH9 25348397 N/A physical interaction ComPPI
HLA-DPA1 KLRG2 25348397 N/A physical interaction ComPPI
HLA-DPA1 CHST11 25348397 N/A physical interaction ComPPI
HLA-DPA1 SAMD1 25348397 N/A physical interaction ComPPI
HLA-DPA1 FKRP 25348397 N/A physical interaction ComPPI
HLA-DPA1 MYO19 25348397 N/A physical interaction ComPPI
HLA-DPA1 BTN2A1 25348397 N/A physical interaction ComPPI
HLA-DPA1 B4GALT5 25348397 N/A physical interaction ComPPI
HLA-DPA1 ERBB3 25348397 N/A physical interaction ComPPI
HLA-DPA1 VWCE 25348397 N/A physical interaction ComPPI
HLA-DPA1 RNF167 25348397 N/A physical interaction ComPPI
HLA-DPA1 FGFRL1 25348397 N/A physical interaction ComPPI
HLA-DPA1 GXYLT2 25348397 N/A physical interaction ComPPI
HLA-DPA1 GLT8D1 25348397 N/A physical interaction ComPPI
HLA-DPA1 POTEF 25348397 N/A physical interaction ComPPI

Visualization










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