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GENE：HPD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HPD
FullNmae 4-hydroxyphenylpyruvate dioxygenase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5147
EnsembleID ENSG00000158104
Uniprot P32754

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HPD immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HPD GO:0000139,GO:0003868,GO:0003868,GO:0003868,GO:0005789,GO:0005829,GO:0006559,GO:0006572,GO:0006572,GO:0006572,GO:0042803,GO:0046872,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HPD hsa:3242 path:hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis - Homo sapiens (human)
HPD hsa:3242 path:hsa00350 Tyrosine metabolism - Homo sapiens (human)
HPD hsa:3242 path:hsa00360 Phenylalanine metabolism - Homo sapiens (human)
HPD hsa:3242 path:hsa01100 Metabolic pathways - Homo sapiens (human)
HPD hsa:3242 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 HPD 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 HPD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 HPD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 HPD 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HPD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CDKN1A HPD 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBMX HPD 25348397 N/A physical interaction ComPPI
HIVEP1 HPD 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
IKBKG HPD 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ASPSCR1 HPD 25348397 N/A physical interaction ComPPI

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