Gene Information gene info

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GENE：HSPB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSPB2
FullNmae heat shock protein family B (small) member 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5247
EnsembleID ENSG00000170276
Uniprot Q16082

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSPB2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSPB2 GO:0005212,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0006986,GO:0007525,GO:0008047,GO:0009408,GO:0042026,GO:0043066,GO:0051082

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HSPB2 hsa:3316 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GZMA HSPB2 23180781 9647220 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR HSPB2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MITF HSPB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 HSPB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA HSPB2 20209605 rna interference,inhibition western blot miRSponge
URS00002075FA HSPB2 20209605 25416803 mrna cleavage,inhibition western blot TarBase
URS00004CD810 HSPB2 25416803 28150434 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
HSPB8 HSPB2 25361965 interaction type N/A PTMCode2
HSPB2 HSPB8 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HOXB9 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2I HSPB2 25348397 N/A physical interaction ComPPI
DAXX HSPB2 25348397 N/A physical interaction ComPPI
CEP19 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG3 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRYAA HSPB2 25348397 N/A physical interaction ComPPI
CRYAB HSPB2 10625651 12601044 23188086 23532854 24234451 25348397 26465331 27898060 physical association two hybrid,nuclear magnetic resonance,physical interaction ComPPI,IntAct,OmniPath
TNNI3 HSPB2 25348397 N/A physical interaction ComPPI
ACTG1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
TRAF6 HSPB2 25348397 N/A physical interaction ComPPI
RPL11 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
RPL36AL HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ACTB HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
MYOZ2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB8 HSPB2 14594798 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,fluorescent resonance energy transfer,physical interaction ComPPI,IntAct
TXNIP HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
AR HSPB2 25348397 N/A physical interaction ComPPI
MAPKAPK5 HSPB2 25348397 N/A physical interaction ComPPI
FHL2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
FLNC HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
CTSB HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
TTN HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
RYR2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
GAPDH HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
CTSD HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
PGM1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
BGN HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ENO1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
PKP2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
PARVA HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
EEF1A1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
DUSP1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
DCTN1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
CFTR HSPB2 25348397 N/A physical interaction ComPPI
TNF HSPB2 25348397 N/A physical interaction ComPPI
C1QA HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
TRAF2 HSPB2 25348397 N/A physical interaction ComPPI
SNX18 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACAA2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
LMO1 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFB1I1 HSPB2 25348397 N/A physical interaction ComPPI
MYBPC3 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
MYOM2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
TCAP HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
POGZ HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NARS1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ATP6V1E1 HSPB2 25348397 N/A physical interaction ComPPI
B2M HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
MT-CO1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
A1CF HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNCA HSPB2 25348397 N/A physical interaction ComPPI
GARS1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
WDR1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
DDIT4 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ABCC9 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
EIF4A2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HNRNPD HSPB2 25348397 N/A physical interaction ComPPI
SNU13 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
TLX3 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF4E HSPB2 25348397 N/A physical interaction ComPPI
DMPK HSPB2 14525934 25348397 9490724 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
EEF2 HSPB2 24234451 25348397 26465331 physical association two hybrid ComPPI,IntAct
HSPB3 HSPB2 10625651 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
HSF1 HSPB2 25348397 N/A physical interaction ComPPI
ZNF335 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
UBL5 HSPB2 25348397 N/A physical interaction ComPPI
CMYA5 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
NDUFA13 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
BICRAL HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ALDH2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
CKM HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
A2M HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
LGALS1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ACTA1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ATP5F1A HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
BEX2 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ENKD1 HSPB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPS11 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
CRYGC HSPB2 25348397 N/A physical interaction ComPPI
ENO3 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ALDOA HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
MT-CO3 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ABCD4 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
MDH1 HSPB2 25348397 N/A physical interaction ComPPI
NDUFA6 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
ETFA HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HADHB HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
EEF1A1P5 HSPB2 25348397 N/A physical interaction ComPPI
MLF2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
MT-CO2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
CYP1B1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
CAPZA2 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
RPL36A HSPB2 25348397 N/A physical interaction ComPPI
ACTC1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 CRYAA2 25348397 N/A physical interaction ComPPI
HSPB2 MYH6 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 MCCC2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 SDHA 25348397 N/A physical interaction ComPPI
HSPB2 AGAP11 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 BEX4 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 THUMPD2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 MB 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 PPM1K 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 SDF2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 SLC2A1 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 TATDN1 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 THEMIS2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 ASAH1 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 DCTN6 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 NT5DC2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
HSPB2 KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPB2 MISP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPB2 RFPL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPB2 PRR35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPB2 VEZF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPB2 GUK1 24234451 25348397 26465331 physical association two hybrid ComPPI,IntAct
CLK4 HSPB2 12705895 14525934 N/A two hybrid HPRD
RPS6KA5 HSPB2 14525934 9687510 N/A experimental interaction detection HPRD
HSPB2 HSPB2 24234451 26465331 physical association two hybrid IntAct
MAPKAPK2 HSPB2 18266962 27898060 stimulant N/A OmniPath
MAPKAPK3 HSPB2 18266962 27898060 stimulant N/A OmniPath
HSPB2 CASP3 18266962 27898060 inhibition N/A OmniPath
HSPB2 AKT1 18266962 27898060 stimulant N/A OmniPath
HSPB2 AKT3 18266962 27898060 stimulant N/A OmniPath
HSPB2 MAPK8 18266962 27898060 inhibition N/A OmniPath

Visualization










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