Gene Information gene info

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GENE：IFITM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFITM1
FullNmae interferon induced transmembrane protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5412
EnsembleID ENSG00000185885
Uniprot P13164

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFITM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IFITM1 GO:0001503,GO:0005515,GO:0005765,GO:0005886,GO:0005886,GO:0005886,GO:0007166,GO:0008285,GO:0009615,GO:0016020,GO:0030336,GO:0032991,GO:0034341,GO:0034341,GO:0035455,GO:0035455,GO:0035456,GO:0035456,GO:0045071,GO:0045071,GO:0045071,GO:0045669,GO:0046597,GO:0046597,GO:0051607,GO:0060337

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IFITM1 hsa:8519 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IFITM1 STAT1 16195385 23180781 23386060 physical association anti tag coimmunoprecipitation InnateDB
IFITM1 STAT2 12244326 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFITM1 IRF9 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFITM1 SMARCA4 12244326 17182572 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFITM1 CD19 24243840 29145629 physical association inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
YBX1 IFITM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 IFITM1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 IFITM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IFITM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000315338 IFITM1 22787204 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000315338 IFITM1 22787204 25416803 27292025 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 IFITM1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001EFBE3 IFITM1 18057241 25416803 mrna cleavage,inhibition array technology TarBase
URS00001B968D IFITM1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 IFITM1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 IFITM1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 IFITM1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C0FCB IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006FDD4 IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000013ABA3 IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C11BC IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000251D0B IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000031602A IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CC20C IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A7F58 IFITM1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CD81 IFITM1 25361965 interaction type N/A PTMCode2
IFITM1 CD81 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CD81 IFITM1 14525934 2398277 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ABHD16A IFITM1 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
IFITM1 CD19 25348397 N/A physical interaction ComPPI
CR2 IFITM1 1383329 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
IFITM1 IFITM1 14525934 14667819 N/A two hybrid HPRD
IFITM1 MEP1B 24234451 27180358 physical association ubiquitin reconstruction IntAct

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