Gene Information gene info

GENE:IFITM3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFITM3
FullNmae interferon induced transmembrane protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5414
EnsembleID ENSG00000142089
Uniprot Q01628

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFITM3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IFITM3 GO:0005515,GO:0005765,GO:0005886,GO:0005886,GO:0005886,GO:0006955,GO:0009615,GO:0031901,GO:0031902,GO:0032897,GO:0032991,GO:0034341,GO:0034341,GO:0035455,GO:0035455,GO:0035456,GO:0035456,GO:0045071,GO:0045071,GO:0046597,GO:0046597,GO:0046597,GO:0048471,GO:0051607,GO:0051607,GO:0060337

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IFITM3 STAT1 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFITM3 STAT2 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFITM3 IRF9 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFITM3 SMARCA4 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFITM3 STAT3 17182572 23180781 physical association anti tag coimmunoprecipitation InnateDB
FYN IFITM3 23180781 24627473 phosphorylation reaction phosphotransferase assay InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 IFITM3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 IFITM3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 IFITM3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 IFITM3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA IFITM3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IFITM3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 IFITM3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IFITM3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 IFITM3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 IFITM3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
KLF4 IFITM3 21531817 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFBE3 IFITM3 18057241 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 IFITM3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C0099 IFITM3 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002ED720 IFITM3 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075D15B IFITM3 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001C85C7 IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000170CF4 IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004AAAFF IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000000EF0B IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000005CE28 IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000334286 IFITM3 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FYN IFITM3 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GLP1R IFITM3 25348397 N/A physical interaction ComPPI
FYN IFITM3 25348397 N/A physical interaction ComPPI
NEDD4 IFITM3 25348397 N/A physical interaction ComPPI
ABHD16A IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FFAR2 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A3 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KIR2DL3 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CD53 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NAMPT IFITM3 18486613 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
ERGIC3 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FKBP7 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGPL1 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RETREG3 IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM14B IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VKORC1 IFITM3 25348397 N/A physical interaction ComPPI
IFITM3 REEP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 FAM210B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 LYPD5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 ELOVL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 SLC10A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 SLC10A2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 GPRC5D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM86B IFITM3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IFITM3 GPR37 24234451 28298427 physical association ubiquitin reconstruction IntAct
IFITM3 PTAFR 24234451 28298427 physical association ubiquitin reconstruction IntAct
FYN IFITM3 23055554 24627473 26354436 27898060 N/A N/A OmniPath

Visualization