Gene Information gene info

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GENE：IMPA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IMPA1
FullNmae inositol monophosphatase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6050
EnsembleID ENSG00000133731
Uniprot P29218

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IMPA1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IMPA1 GO:0000287,GO:0005515,GO:0005737,GO:0005829,GO:0006020,GO:0006021,GO:0006661,GO:0006796,GO:0007165,GO:0007165,GO:0008934,GO:0008934,GO:0008934,GO:0030145,GO:0031403,GO:0042802,GO:0042803,GO:0046854,GO:0052832,GO:0052833,GO:0052834

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IMPA1 hsa:3612 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
IMPA1 hsa:3612 path:hsa01100 Metabolic pathways - Homo sapiens (human)
IMPA1 hsa:3612 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 IMPA1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 IMPA1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 IMPA1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 IMPA1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HNF4A IMPA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 IMPA1 22301190 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000EED18 IMPA1 22301190 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000028BB8 IMPA1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 IMPA1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 IMPA1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000031B6ED IMPA1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B341F IMPA1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000195F5B IMPA1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 IMPA1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 IMPA1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 IMPA1 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BRAP IMPA1 25361965 interaction type N/A PTMCode2
IMPA1 BRAP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
S100B IMPA1 19593677 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CYCS IMPA1 25348397 N/A physical interaction ComPPI
ARHGDIA IMPA1 25348397 N/A physical interaction ComPPI
DUT IMPA1 25348397 N/A physical interaction ComPPI
NTRK1 IMPA1 25348397 N/A physical interaction ComPPI
TXN IMPA1 25348397 N/A physical interaction ComPPI
EIF6 IMPA1 25348397 N/A physical interaction ComPPI
ELAVL1 IMPA1 25348397 N/A physical interaction ComPPI
IMPA1 CALB1 12176979 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
IMPA1 NXF1 25348397 N/A physical interaction ComPPI
IMPA1 IMPA2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IMPA1 NUDT9 25348397 N/A physical interaction ComPPI
IMPA1 PGLS 25348397 N/A physical interaction ComPPI
IMPA1 ISCU 25348397 N/A physical interaction ComPPI
IMPA1 PHPT1 25348397 N/A physical interaction ComPPI
IMPA1 SCPEP1 25348397 N/A physical interaction ComPPI
IMPA1 UGDH 25348397 N/A physical interaction ComPPI
IMPA1 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
IMPA1 IMPA1 1332026 1377913 14525934 16189514 19447967 21516116 24234451 25416956 8068620 8068621 physical association two hybrid,experimental interaction detection,two hybrid array,two hybrid pooling approach,two hybrid HPRD,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009AF657 IMPA1 27087310 direct interaction,inhibition N/A NPInter

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