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GENE：KLKB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KLKB1
FullNmae kallikrein B1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6371
EnsembleID ENSG00000164344
Uniprot P03952

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KLKB1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KLKB1 GO:0002542,GO:0004252,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005886,GO:0006508,GO:0007596,GO:0031638,GO:0031639,GO:0042730,GO:0051919,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KLKB1 hsa:3818 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 KLKB1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 KLKB1 15517885 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KLKB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AATF KLKB1 23146908 trascriptional regulation,stimulation inferred by curator TFlink
AR KLKB1 10547578 11006269 11059779 11238180 11504717 11532861 11571582 12376473 12539223 12648523 12651911 12958311 15368351 15543614 15557561 15640095 16342680 16425097 16434977 16724108 17011549 17075604 17094454 17426252 17433535 17566103 18780293 18829551 19274665 20069563 21308712 21780100 21981678 22179832 22245379 22473899 23667504 23884959 24307657 24937452 7514587 8626436 9052414 9211894 9316650 trascriptional regulation,stimulation inferred by curator TFlink
BTG2 KLKB1 21172304 trascriptional regulation,stimulation inferred by curator TFlink
EP300 KLKB1 23884959 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 KLKB1 18640093 trascriptional regulation,stimulation inferred by curator TFlink
FUS KLKB1 21909421 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A KLKB1 23884959 trascriptional regulation,stimulation inferred by curator TFlink
NCOA4 KLKB1 18649734 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 KLKB1 11909978 15517885 trascriptional regulation,stimulation inferred by curator TFlink
NKX3-1 KLKB1 17483333 trascriptional regulation,stimulation inferred by curator TFlink
PA2G4 KLKB1 16254079 trascriptional regulation,stimulation inferred by curator TFlink
PGR KLKB1 9052414 trascriptional regulation,stimulation inferred by curator TFlink
REL KLKB1 17011549 trascriptional regulation,stimulation inferred by curator TFlink
RELA KLKB1 15517885 trascriptional regulation,stimulation inferred by curator TFlink
RREB1 KLKB1 17550981 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 KLKB1 16237704 trascriptional regulation,stimulation inferred by curator TFlink
RUNX2 KLKB1 16237704 trascriptional regulation,stimulation inferred by curator TFlink
SIN3A KLKB1 16254079 trascriptional regulation,stimulation inferred by curator TFlink
SP1 KLKB1 15708372 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 KLKB1 15708372 trascriptional regulation,stimulation inferred by curator TFlink
SP3 KLKB1 15708372 trascriptional regulation,stimulation inferred by curator TFlink
SPDEF KLKB1 16237704 17483333 trascriptional regulation,stimulation inferred by curator TFlink
SRCAP KLKB1 20432434 trascriptional regulation,stimulation inferred by curator TFlink
TRPS1 KLKB1 14680804 trascriptional regulation,stimulation inferred by curator TFlink
WT1 KLKB1 18631392 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KLKB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
KLKB1 KNG1 25361965 interaction type N/A PTMCode2
KNG1 KLKB1 25361965 interaction type N/A PTMCode2
TFPI2 KLKB1 25361965 interaction type N/A PTMCode2
KLKB1 TFPI2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KNG1 KLKB1 10464316 14525934 25348397 291905 500690 7686159 7944388 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TFPI2 KLKB1 14525934 25348397 8555184 N/A experimental interaction detection,in vitro ComPPI,HPRD
SERPINA5 KLKB1 11864713 14525934 25348397 2551064 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
HGFAC KLKB1 14525934 25348397 8226803 N/A experimental interaction detection,in vitro ComPPI,HPRD
KLKB1 F12 14525934 25348397 3521732 N/A experimental interaction detection,in vitro ComPPI,HPRD
KLKB1 HGF 10962009 12372819 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KLKB1 IGFBP3 10226805 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
KLKB1 GPHN 25348397 N/A physical interaction ComPPI
KLKB1 ZBTB1 25348397 N/A physical interaction ComPPI
KLKB1 NCAPH 25348397 N/A physical interaction ComPPI
KLKB1 CNOT2 25348397 N/A physical interaction ComPPI
KLKB1 MST1 10068459 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
TRADD KLKB1 24234451 30561431 association virotrap IntAct
KLKB1 PRKAG1 18353705 27898060 stimulant N/A OmniPath

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