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GENE：KLRC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KLRC2
FullNmae killer cell lectin like receptor C2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6375
EnsembleID ENSG00000205809
Uniprot P26717

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KLRC2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KLRC2 GO:0002223,GO:0002223,GO:0002228,GO:0002250,GO:0004888,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0006968,GO:0007165,GO:0009897,GO:0023024,GO:0030246,GO:0032814,GO:0043235,GO:0043235,GO:0043323,GO:0045954,GO:0045954,GO:0062081,GO:1990405

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KLRC2 hsa:3822 path:hsa04612 Antigen processing and presentation - Homo sapiens (human)
KLRC2 hsa:3822 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HLA-E KLRC2 11015446 12731048 20814939 23715743 24586048 26192618 2731048 9486650 9625766 9655483 interaction type N/A ACSN
KLRD1 KLRC2 11015446 12731048 18448674 20814939 23180781 23715743 24586048 26192618 2731048 9486650 9625766 9655483 interaction type,physical association surface plasmon resonance ACSN,InnateDB
KLRC2 SYK 11015446 12731048 20814939 23715743 24586048 26192618 2731048 9486650 9625766 9655483 interaction type N/A ACSN
KLRC2 TYROBP 15845448 20890284 23180781 physical association anti tag coimmunoprecipitation,nuclear magnetic resonance InnateDB
TYROBP KLRC2 15845448 20890284 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
FOXA1 KLRC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 KLRC2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 KLRC2 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
FBP1 KLRC2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TYROBP KLRC2 20890284 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HLA-G KLRC2 18083576 24234451 25348397 physical association surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
HLA-E KLRC2 14525934 18083576 24234451 25348397 9103421 9486650 physical association experimental interaction detection,surface plasmon resonance,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
KLRD1 KLRC2 10320637 14525934 18083576 24234451 25348397 physical association experimental interaction detection,surface plasmon resonance,physical interaction,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
KLRD1 KLRC2 10320637 18448674 27898060 8943374 9486650 N/A N/A OmniPath

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