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GENE：MFGE8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MFGE8
FullNmae milk fat globule EGF and factor V/VIII domain containing
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7036
EnsembleID ENSG00000140545
Uniprot Q08431

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MFGE8 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MFGE8 GO:0001525,GO:0001786,GO:0002080,GO:0005178,GO:0005201,GO:0005576,GO:0005615,GO:0005788,GO:0007155,GO:0007338,GO:0009897,GO:0016020,GO:0043277,GO:0062023,GO:0070062,GO:1903561

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MFGE8 hsa:4240 path:hsa04148 Efferocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MFGE8 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MFGE8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 MFGE8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MFGE8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MFGE8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MFGE8 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000BE495 MFGE8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003AD80B MFGE8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FF522 MFGE8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032D69B MFGE8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D15B MFGE8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004E008F MFGE8 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ITGB5 MFGE8 25348397 N/A physical interaction ComPPI
PDGFRB MFGE8 25348397 N/A physical interaction ComPPI
MYC MFGE8 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ABCE1 MFGE8 25348397 N/A physical interaction ComPPI
FUS MFGE8 25348397 N/A physical interaction ComPPI
YTHDF1 MFGE8 25348397 N/A physical interaction ComPPI
PLEKHA7 MFGE8 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
MFGE8 PDGFRB 21868707 27898060 N/A N/A OmniPath
MFGE8 ITGB3 24441829 27898060 N/A N/A OmniPath
MFGE8 ITGAV 24441829 27898060 N/A N/A OmniPath

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