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GENE：MIB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MIB1
FullNmae MIB E3 ubiquitin protein ligase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21086
EnsembleID ENSG00000101752
Uniprot Q86YT6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MIB1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MIB1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MIB1 GO:0001568,GO:0001701,GO:0001756,GO:0001841,GO:0001947,GO:0004842,GO:0005515,GO:0005737,GO:0005813,GO:0005829,GO:0005886,GO:0006511,GO:0006897,GO:0007219,GO:0008270,GO:0016567,GO:0016567,GO:0030182,GO:0031410,GO:0045665,GO:0045807,GO:0061630

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MIB1 hsa:57534 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AZI2 MIB1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
TBK1 MIB1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
MIB1 MIB1 12530964 16140393 18043734 26467481 ubiquitination reaction,up-regulates activity N/A Signor
MIB1 JAG1 12530964 20720151 21071413 23331499 stimulation N/A SignaLink,SignaLink
MIB1 DL 15829515 22162135 23331499 ubiquitination reaction,stimulation N/A SignaLink,SignaLink,SignaLink
MIB1 SER 15930117 23331499 stimulation N/A SignaLink,SignaLink
MIB1 JAG1A 20573700 stimulation N/A SignaFish
MIB1 JAG1B 20573700 stimulation N/A SignaFish
MIB1 M4MD44 23342113 stimulation N/A SignaFish
MIB1 DLA 15013799 stimulation N/A SignaFish

Source Target Pmid Interactiontype Methods Database
AR MIB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 MIB1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000055128B MIB1 19826008 25416803 mrna cleavage,inhibition array technology,rna immunoprecipitation,quantitative reverse transcription pcr TarBase
URS00000F31F4 MIB1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 MIB1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D MIB1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00000AA464 MIB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 MIB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000076E54 MIB1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 MIB1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 MIB1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 MIB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E MIB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 MIB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D MIB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 MIB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 MIB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E732F MIB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 MIB1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MIB1 DAPK1 25361965 interaction type N/A PTMCode2
DAPK1 MIB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPRE1 MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLL1 MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CEP43 MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2D1 MIB1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SMN1 MIB1 25348397 N/A physical interaction ComPPI
UBE2D4 MIB1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DAB2 MIB1 11812785 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
DLL1 MIB1 25348397 N/A physical interaction ComPPI
UBE2D2 MIB1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPN22 MIB1 25348397 N/A physical interaction ComPPI
UBC MIB1 25348397 N/A physical interaction ComPPI
UBE2N MIB1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NTRK1 MIB1 25348397 N/A physical interaction ComPPI
MYC MIB1 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CEP135 MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BLM MIB1 25348397 N/A physical interaction ComPPI
RBBP4 MIB1 25348397 N/A physical interaction ComPPI
EPN3 MIB1 25348397 N/A physical interaction ComPPI
RANGAP1 MIB1 25348397 N/A physical interaction ComPPI
TOP3B MIB1 25348397 N/A physical interaction ComPPI
PCNT MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PER3 MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GABARAP MIB1 24234451 25348397 28712572 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
SSX2IP MIB1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CENPJ MIB1 25348397 N/A physical interaction ComPPI
LPXN MIB1 25348397 N/A physical interaction ComPPI
CMIP MIB1 25348397 N/A physical interaction ComPPI
UBE2D3 MIB1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TBK1 MIB1 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK4 MIB1 25348397 N/A physical interaction ComPPI
DDB1 MIB1 25348397 N/A physical interaction ComPPI
MIB1 SNX5 14525934 16857196 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MIB1 UBE2U 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MIB1 UBE2W 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MIB1 JAG1 25348397 N/A physical interaction ComPPI
MIB1 RYK 25348397 N/A physical interaction ComPPI
MIB1 AZI2 25348397 N/A physical interaction ComPPI
MIB1 PCM1 21956701 24121310 24234451 25348397 25795303 26638075 27898060 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct,OmniPath
MIB1 DAPK1 12351649 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
MIB1 CEP131 25348397 N/A physical interaction ComPPI
MIB1 USP9X 25348397 N/A physical interaction ComPPI
MIB1 ZFC3H1 25348397 N/A physical interaction ComPPI
MIB1 ZBTB10 25348397 N/A physical interaction ComPPI
MIB1 GEMIN4 25348397 N/A physical interaction ComPPI
MIB1 MCM3 25348397 N/A physical interaction ComPPI
MIB1 TOP3A 25348397 N/A physical interaction ComPPI
MIB1 MCM7 25348397 N/A physical interaction ComPPI
MIB1 CDC27 25348397 N/A physical interaction ComPPI
MIB1 CEP250 25348397 N/A physical interaction ComPPI
MIB1 FSD1 25348397 N/A physical interaction ComPPI
MIB1 MED4 25348397 N/A physical interaction ComPPI
MIB1 CEP290 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MIB1 CEP162 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MIB1 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MIB1 CNTRL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MIB1 POC5 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MIB1 OFD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MIB1 CCDC14 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MIB1 TPTE2 25348397 N/A physical interaction ComPPI
MIB1 LRRCC1 25348397 N/A physical interaction ComPPI
MIB1 CHRNA3 25348397 N/A physical interaction ComPPI
MIB1 FAM171B 25348397 N/A physical interaction ComPPI
MIB1 ANKRD55 25348397 N/A physical interaction ComPPI
MIB1 EPB41L4A 25348397 N/A physical interaction ComPPI
MIB1 EPB41L5 25348397 N/A physical interaction ComPPI
MIB1 MIB2 21903422 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MIB1 ZFYVE1 24234451 25348397 28712572 association anti tag coimmunoprecipitation ComPPI,IntAct
DL MIB1 25348397 N/A physical interaction ComPPI
SER MIB1 25348397 N/A physical interaction ComPPI
FT MIB1 24234451 25215488 25348397 physical association two hybrid ComPPI,IntAct
N MIB1 25348397 N/A physical interaction ComPPI
TANK MIB1 24234451 30561431 association virotrap IntAct
DLD MIB1 15013799 17196985 27898060 N/A N/A OmniPath
MIB1 DLL1 15824097 16000382 16140393 16857196 23162128 27898060 stimulant N/A OmniPath
MIB1 JAG1 12530964 18043734 27898060 stimulant N/A OmniPath
MIB1 TBK1 21903422 27898060 N/A N/A OmniPath
TBK1 MIB1 21903422 27898060 N/A N/A OmniPath
MIB1 DAPK1 12351649 27898060 inhibition N/A OmniPath
MIB1 DLL4 16000382 16140393 23162128 27898060 stimulant N/A OmniPath
AZI2 MIB1 21903422 27898060 N/A N/A OmniPath
MIB1 DLL3 16140393 27898060 stimulant N/A OmniPath
MIB1 RYK 21875946 27898060 inhibition N/A OmniPath
MIB1 SMN1 23615451 27898060 inhibition N/A OmniPath

Visualization










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