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GENE：MNAT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MNAT1
FullNmae MNAT1 component of CDK activating kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7181
EnsembleID ENSG00000020426
Uniprot P51948

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MNAT1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MNAT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MNAT1 GO:0000079,GO:0000082,GO:0000439,GO:0005515,GO:0005654,GO:0005654,GO:0005675,GO:0005675,GO:0006281,GO:0006289,GO:0006357,GO:0006357,GO:0006366,GO:0006366,GO:0007512,GO:0008270,GO:0019907,GO:0021591,GO:0043066,GO:0048661,GO:0051592,GO:0061575,GO:0065003,GO:0070516,GO:0070985,GO:1905775,GO:2000045

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MNAT1 hsa:4331 path:hsa03022 Basal transcription factors - Homo sapiens (human)
MNAT1 hsa:4331 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDK7 MNAT1 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 26192618 7533895 interaction type N/A ACSN
ERCC1 MNAT1 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 26192618 7533895 interaction type N/A ACSN
MNAT1 XAB2 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 26192618 7533895 interaction type N/A ACSN
MNAT1 XPA 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 26192618 7533895 interaction type N/A ACSN
RPA2 MNAT1 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 26192618 7533895 interaction type N/A ACSN
MNAT1 CDK1 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 26192618 7533895 interaction type N/A ACSN
MNAT1 CDK2 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 26192618 7533895 interaction type N/A ACSN
MNAT1 TSC1 17355907 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR MNAT1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MNAT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MNAT1 19151767 20596676 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MNAT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MTA1 MNAT1 12527756 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 MNAT1 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
MNAT1 TP53 25361965 interaction type N/A PTMCode2
TP53 MNAT1 25361965 interaction type N/A PTMCode2
MNAT1 GTF2H2 25361965 interaction type N/A PTMCode2
GTF2H2 MNAT1 25361965 interaction type N/A PTMCode2
MNAT1 MTA1 25361965 interaction type N/A PTMCode2
MTA1 MNAT1 25361965 interaction type N/A PTMCode2
MNAT1 GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 MNAT1 25361965 interaction type N/A PTMCode2
MNAT1 ERCC2 25361965 interaction type N/A PTMCode2
ERCC2 MNAT1 25361965 interaction type N/A PTMCode2
CCNH MNAT1 25361965 interaction type N/A PTMCode2
MNAT1 CCNH 25361965 interaction type N/A PTMCode2
CDK7 MNAT1 25361965 interaction type N/A PTMCode2
MNAT1 CDK7 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 MNAT1 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH MNAT1 17353931 24234451 25348397 26340423 8521818 phosphorylation reaction,physical association anti bait coimmunoprecipitation,cross-linking study,physical interaction,protein kinase assay ComPPI,IntAct
TRIM21 MNAT1 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TP53BP1 MNAT1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
ERCC3 MNAT1 14525934 25348397 9118947 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MKRN3 MNAT1 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
H2BC4 MNAT1 25348397 N/A physical interaction ComPPI
MAGEC2 MNAT1 25348397 N/A physical interaction ComPPI
RNF7 MNAT1 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SP1 MNAT1 25348397 N/A physical interaction ComPPI
RB1 MNAT1 11113200 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
GTF2H1 MNAT1 24234451 25348397 26340423 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
E2F1 MNAT1 10428966 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RPA1 MNAT1 25348397 N/A physical interaction ComPPI
EEF1A1 MNAT1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CILK1 MNAT1 25348397 N/A physical interaction ComPPI
RPA2 MNAT1 25348397 N/A physical interaction ComPPI
RPA3 MNAT1 25348397 N/A physical interaction ComPPI
MNAT1 GTF2E2 11113176 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MNAT1 MTA1 12527756 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
MNAT1 CDK7 14525934 23602568 24234451 25348397 29568061 8521393 8521818 9130708 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo,tandem affinity purification,proximity-dependent biotin identification ComPPI,HPRD,IntAct
MNAT1 BRCA1 14525934 15282296 22493164 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro ComPPI,HPRD,IntAct
MNAT1 MCM7 11056214 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
MNAT1 HPS6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MNAT1 RBM48 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MNAT1 COPS6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MNAT1 LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MNAT1 ESR1 10949034 12527756 14525934 25348397 8308015 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MNAT1 POU2F1 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
MNAT1 POU2F2 14525934 25348397 9368058 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MNAT1 POU5F1 14525934 25348397 9368058 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MNAT1 EEF1A1P5 25348397 N/A physical interaction ComPPI
MNAT1 TP53 14525934 25348397 9372954 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MNAT1 DMAP1 25348397 N/A physical interaction ComPPI
MNAT1 GTF2H2 25348397 N/A physical interaction ComPPI
MNAT1 ERCC2 25348397 N/A physical interaction ComPPI
MNAT1 GTF2H3 25348397 N/A physical interaction ComPPI
MNAT1 GTF2H4 25348397 N/A physical interaction ComPPI
MNAT1 USP2 25348397 N/A physical interaction ComPPI
MNAT1 POLR2A 25348397 N/A physical interaction ComPPI
MNAT1 SUPT5H 25348397 N/A physical interaction ComPPI
MNAT1 NKX3-1 25348397 N/A physical interaction ComPPI
MNAT1 TRIM2 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TRIM9 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TRIML1 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TRIM31 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TRIM34 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 RNF32 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TRIM17 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 RNF41 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TRIM39 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TRIM5 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 MDM4 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 BEX3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MNAT1 CDK2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MNAT1 SFR1 25348397 N/A physical interaction ComPPI
MNAT1 H2BC11 25348397 N/A physical interaction ComPPI
MNAT1 PCIF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MNAT1 GTF2H5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MNAT1 MAGEE2 25348397 N/A physical interaction ComPPI
MNAT1 SIRT6 25348397 N/A physical interaction ComPPI
MNAT1 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MNAT1 TSC1 17355907 24234451 25348397 physical association two hybrid ComPPI,IntAct
MNAT1 CDK8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRIM26 MNAT1 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MNAT1 TSC1 17355907 27898060 N/A N/A OmniPath
TSC1 MNAT1 17355907 27898060 N/A N/A OmniPath

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